In Christian Doppler laboratories, application-orientated basic research is carried out at a high level, with outstanding scientists cooperating with innovative companies. The Christian Doppler Research Association is internationally recognised as a best-practice example for the promotion of this cooperation.

Christian Doppler Laboratories are jointly funded by the public sector and the participating companies. The most important public funding body is the Federal Ministry of Labour and Economic Affairs (BMAW).

CHRISTIAN DOPPLER LABORATORY FOR INNOVATIVE CRYSTAL ENGINEERING STRATEGIES IN DRUG DEVELOPMENT

The CD Laboratory is dedicated to exploring critical material properties of active pharmaceutical ingredients (APIs) and excipients that are essential for the production, quality, and safety of medicines. By optimising these properties, manufacturing processes can be streamlined and ultimately the costs of essential pharmaceutical products will be reduced.

Most APIs consist of small molecules, which are usually processed into tablets in crystalline form due to their superior chemical stability. However, the increasing complexity of modern drug molecules often results in reduced water solubility. "Crystal engineering", a material science technique, has the possibility to enable the development of diverse solid-state forms with advantageous pharmaceutical properties. The goal is to identify the optimal solid-state form(s) of biologically active molecules in terms of stability, solubility, and processability, paving the way for their development into high-quality, market-ready drugs.

The members of the CD Laboratory investigate molecular interactions and their impact on the chemical stability, processability, and efficacy of pharmaceutical compounds. By combining experimental and computational methods, we not only optimize material properties but also develop innovative approaches for in silico solid-form discovery and advanced stabilization techniques for forms with enhanced bioavailability. Special focus is placed on the interactions between APIs and excipients, enabling the design of customized pharmaceutical formulations.

Josef-Moeller-Haus, Innrain 52
6020 Innsbruck

Please register at Registration by 17 March 2025 at the latest.

We look forward to seeing you there!