Cornelia KARG, Mag. pharm. Dr.
Senior Scientist
Contact
Institute of Pharmacy/Pharmacognosy
University of Innsbruck
Center for Chemistry and Biomedicine
Innrain 80 - 82/IV
Room: L.04.042
6020 Innsbruck / Austria
Phone: +43 512 507 - 58408
Email: cornelia.karg@uibk.ac.at
Research
- Isolation and structural characterization of natural products derived from chlorophyll breakdown in plants, investigations on the molecular mode of action in healthy and cancer cells
- Investigations on pharmacokinetic properties of bioactive natural products from plants and plant-based food
- Studies on the effects and mode of action of UV-protective natural products
Publication List
ORCID:https://orcid.org/0009-0007-9294-586X
2023
Karg, C. A., Taniguchi, M., Lindsey, J. S., and Moser, S. (2023) Phyllobilins – Bioactive Natural Products Derived from Chlorophyll – Plant Origins, Structures, Absorption Spectra, and Biomedical Properties, Planta Med 89, 637-662, doi.org/10.1055/a-1955-4624
2022
Karg, C. A., Parráková, L., Fuchs, D., Schennach, H., Kräutler, B., Moser, S. et al. (2022) A Chlorophyll-Derived Phylloxanthobilin Is a Potent Antioxidant That Modulates Immunometabolism in Human PBMC, Antioxidants (Basel) 11, doi.org/10.3390/antiox11102056
Neubig, C. M., Roosen, J., Karg, C. A., and Moser, S. (2022) It’s safe and healthy! Increasing consumers’ willingness to consume aging produce Food Quality and Preference 101, 104608, doi.org/10.1016/j.foodqual.2022.104608
Wang, P., Klassmüller, T., Karg, C. A., Kretschmer, M., Zahler, S., Braig, S. et al. (2022) Using the yeast three-hybrid system for the identification of small molecule-protein interactions with the example of ethinylestradiol, Biol Chem 403, 421-431, doi.org/10.1515/hsz-2021-0355
Karg, C. A., and Moser, S. (2022) Je bunter, desto bioaktiver, Nachrichten aus der Chemie 70, 65-68, doi.org/10.1002/nadc.20224119948
2021
Karg, C. A., Wang, S., Al Danaf, N., Pemberton, R. P., Bernard, D., Kretschmer, M. et al. (2021) Tetrapyrrolic Pigments from Heme- and Chlorophyll Breakdown are Actin-Targeting Compounds, Angew Chem Int Ed Engl 60, 22578-22584, doi.org/10.1002/anie.202107813
Karg, C. A., Neubig, C. M., Roosen, J., and Moser, S. (2021) Rising levels of antioxidative phyllobilins in stored agricultural produce and their impact on consumer acceptance, npj Sci Food 5, 19, doi.org/10.1038/s41538-021-00101-7
Karg, C. A., Doppler, C., Schilling, C., Jakobs, F., Dal Colle, M. C. S., Frey, N. et al. (2021) A yellow chlorophyll catabolite in leaves of Urtica dioica L.: An overlooked phytochemical that contributes to health benefits of stinging nettle, Food chemistry 359, 129906, doi.org/10.1016/j.foodchem.2021.129906
Wang, P., Karg, C. A., Frey, N., Frädrich, J., Vollmar, A. M., andMoser, S. (2021) Phyllobilins as a challenging diverse natural product class: Exploration of pharmacological activities, Arch Pharm 354, 2100061, doi.org/10.1002/ardp.202100061
2020
Karg, C. A., Wang, P., Kluibenschedl, F., Müller, T., Allmendinger, L., Vollmar, A. M. et al. (2020) Phylloxanthobilins are Abundant Linear Tetrapyrroles from Chlorophyll Breakdown with Activities Against Cancer Cells, Eur J Org Chem 4499-4509, doi.org/10.1002/ejoc.202000692
2019
Karg, C. A., Schilling, C. M., Allmendinger, L., and Moser, S. (2019) Isolation, characterization, and antioxidative activity of a dioxobilin-type phylloxanthobilin from savoy cabbage, J Porphyr Phthalocyanines 23, 881-888, doi.org/10.1142/s1088424619500718
Karg, C. A., Wang, P., Vollmar, A. M., and Moser, S. (2019) Re-opening the stage for Echinacea research - Characterization of phylloxanthobilins as a novel anti-oxidative compound class in Echinacea purpurea, Phytomedicine 60, 152969, doi.org/10.1016/j.phymed.2019.152969
Teaching activities
- Quality control of medicinal plants, UE
- Bachelor´s Thesis in Pharmacy, PS