Publications

  1. Akkuş-Dağdeviren Z.B., Arısoy S, Friedl JD, Fürst A, Saleh A, Bernkop-Schnürch A. (2023). Polyphosphate coated nanoparticles: Enzyme-activated charge-reversal gene delivery systems. Int. J. Pharm., 646, 123474.
  2. Akkuş-Dağdeviren, Z.B.; Fürst, A.; Friedl, D.J.; Tribus, M.; Bernkop-Schnürch, A. (2023). Nanoarchitectonics of Layer-by-Layer (LbL) coated nanostructured lipid carriers (NLCs) for Enzyme-Triggered charge reversal. J. Colloid & Interface Sci., 629(Pt A), 541-553.
  3. Akkuş-Dağdeviren, Z.B.; Saleh, A.; Schöpf, C.; Truszkowska, M.; Bratschun-Khan, D.; Fürst ,A.; Seybold, A.; Offterdinger, M.; Marx, F.; Bernkop-Schnürch, A. (2023). Phosphatase-degradable nanoparticles: A game-changing approach for the delivery of antifungal proteins. J. Colloid & Interface Sci., 646, 290-300.
  4. Claus, V.; Sandmeier, M.; Hock, N.; Spleis, H.; Lindner, S.; Kalb, M.; Bernkop-Schnürch, A. (2023). Counterion optimization for hydrophobic ion pairing (HIP): Unraveling the key factors. Int. J. Pharm., 647, 123507.
  5. Claus, V.; Spleis, H.; Federer, C.; Zöller, K.; Wibel, R.; Laffleur, F.; Dumont, C.; Caisse, P.; Bernkop-Schnürch, A. (2023). Self-emulsifying drug delivery systems (SEDDS): In vivo-proof of concept for oral delivery of insulin glargine. Int. J. Pharm., 639, 122964.
  6. Efiana, N.A.; Kali, G.; Fürst, A.; Dizdarević, A.; Bernkop-Schnürch, A. (2023). Betaine-modified hydroxyethyl cellulose (HEC): A biodegradable mucoadhesive polysaccharide exhibiting quaternary ammonium substructures. Eur. J. Pharm. Sci., 180, 106313.
  7. Fürst, A.; Kali, G.; Efiana, N.A.; Akkuş-Dağdeviren, Z.B.; Haddadzadegan, S.; Bernkop-Schnürch, A. (2023). Thiolated cyclodextrins: A comparative study of their mucoadhesive properties. Int. J. Pharm., 635, 122719.
  8. Fürst, A.; Shahzadi, I.; Akkuş-Dağdeviren, Z.B.; Schöpf, A.M.; Gust, R.; Bernkop-Schnürch, A. (2023). Zeta potential shifting nanoemulsions comprising single and gemini tyrosine-based surfactants. Eur. J. Pharm. Sci., 189, 106538.
  9. Haddadzadegan, S.; Knoll, P.; Wibel, R.; Kali, G.; Bernkop-Schnürch, A. (2023). Three generations of thiolated cyclodextrins: A direct comparison of their mucus permeating and mucoadhesive properties. Acta Biomater., 167, 309-320.
  10. Hock, N.; To, D.; Sanchez Armengol, E.; Summonte, S.; Seybold, A.; Federer, C.; Bernkop-Schnürch, A. (2023). Design of biodegradable nanoparticles for enzyme-controlled long-acting drug release. Journal of Drug Delivery Science and Technology
  11. Jörgensen, A.M.; Steinbring, C.; Stengel, D.; To, D.; Schmid, P.; Bernkop-Schnürch, A. (2023). Self-Emulsifying Drug Delivery Systems (SEDDS) Containing Reverse Micelles: Advanced Oral Formulations for Therapeutic Peptides. Adv Healthc. Mater (31):e2302034.
  12. Jörgensen, A.M.; Wibel, R.; Bernkop-Schnürch, A. (2023). Biodegradable Cationic and Ionizable Cationic Lipids: A Roadmap for Safer Pharmaceutical Excipients. Small, 19(17), e2206968.
  13. Jörgensen, A.M.; Wibel, R.; Veider, F.; Hoyer, B.; Chamieh, J.; Cottet, H.; Bernkop-Schnürch, A. (2023). Self-emulsifying drug delivery systems (SEDDS): How organic solvent release governs the fate of their cargo. Int. J. Pharm., 647, 123534.
  14. Jörgensen, A.M.; Knoll, P.; Haddadzadegan, S.; Fabian, H.; Hupfauf, A.; Gust, R.; Georg Jörgensen, R.; Bernkop-Schnürch, A. (2023). Biodegradable arginine based steroid-surfactants: Cationic green agents for hydrophobic ion-pairing. Int. J. Pharm., 630, 122438.
  15. Kali, G.; Fürst, A.; Efiana, N.A.; Dizdarević, A.; Bernkop-Schnürch, A. (2023). Intraoral Drug Delivery: Highly Thiolated κ-Carrageenan as Mucoadhesive Excipient. Pharmaceutics, 15 (7), 1993.
  16. Kali, G.; Haddadzadegan, S.; Laffleur, F.; Bernkop-Schnürch, A. (2023). Per-thiolated cyclodextrins: Nanosized drug carriers providing a prolonged gastrointestinal residence time. Carbohydr. Polym., 300, 120275.
  17. Kali, G.; Özkahraman, B.; Laffleur, F.; Knoll, P.; Wibel, R.; Zöller, K.; Bernkop-Schnürch, A. (2023). Thiolated Cellulose: A Dual-Acting Mucoadhesive and Permeation-Enhancing Polymer. Biomacromolecules, 24(11), 4880-4889.
  18. Kaplan, Ö.; Truszkowska, M.; Kali, G.; Knoll, P.; Blanco Massani, M.; Braun, D.E.; Bernkop-Schnürch, A. (2023). Thiolated α-cyclodextrin: The likely smallest drug carrier providing enhanced cellular uptake and endosomal escape. Carbohydr. Polym., 316, 121070.
  19. Knoll, P.; Racaniello, G.F.; Laquintana, V.; Veider, F.; Saleh, A.; Seybold, A.; Denora, N.; Bernkop-Schnürch, A. (2023). Lipid-based nanoparticles: Enhanced cellular uptake via surface thiolation. Int. J. Pharm., 635, 122753.
  20. Le-Vinh, B.; Steinbring, C.; Nguyen Le, N.M.; Matuszczak, B.; Bernkop-Schnürch, A. (2023). S-Protected Thiolated Chitosan versus Thiolated Chitosan as Cell Adhesive Biomaterials for Tissue Engineering. ACS Appl. Mater. Interfaces, 15(34), 40304-40316.
  21. Noreen, S.; Bernkop‐Schnürch, A. (2023). Thiolated Poly‐and Oligosaccharide‐Based Hydrogels for Tissue Engineering and Wound Healing. Advanced Functional Materials 23, S. 2310129.
  22. Saleh, A.; Akkus-Dagdeviren, Z.B.; Haddadzadegan, S.; Wibel, R.; Bernkop-Schnürch, A. (2023). Peptide Antibiotic-Polyphosphate Nanoparticles: A Promising Strategy to Overcome the Enzymatic and Mucus Barrier of the Intestine. Biomacromolecules, 24(6), 2587-2595.
  23. Spleis, H.; Federer, C.; Claus, V.; Sandmeier, M.; Bernkop-Schnürch, A. (2023). Hydrophobic Ion Pairing of Small Molecules: How to Minimize Premature Drug Release from SEDDS and Reach the Absorption Membrane in Intact Form. ACS Biomater. Sci. Eng., 9(3), 1450-1459.
  24. Spleis, H.; Sandmeier, M.; Claus, V.; Bernkop-Schnürch, A. (2023). Surface design of nanocarriers: Key to more efficient oral drug delivery systems. Adv. Colloid Interface Sci., 313, 102848.
  25. Stengel, D.; Demirel, B.H.; Knoll, P.; Truszkowska, M.; Laffleur, F.; Bernkop-Schnürch, A. (2023). PEG vs. zwitterions: How these surface decorations determine cellular uptake of lipid-based nanocarriers. J. Colloid & Interface Sci., 647, 52-64.
  26. To, D.; Kakar, A.; Kali, G.; Wibel, R.; Knoll, P.; Marx, F.; Bernkop-Schnürch, A. (2023). Iminated aminoglycosides in self-emulsifying drug delivery systems: Dual approach to break down the microbial defense. J. Colloid & Interface Sci., 630(Pt B), 164-178.
  27. To, D.; Kali, G.; Haddadzadegan, S.; Jörgensen, A.M.; Nigl, K.; Ricci, F.; Bernkop-Schnürch, A. (2023). Power-Up for Mucoadhesiveness: Two Generations of Thiolated Surfactants for Enhanced Sticky Nanoemulsions. ACS Biomater. Sci. Eng., 9(12), 6797-6804.
  28. Veider, F.; Knoll, P.; Jörgensen, A.M.; Stengel, D.; Bernkop-Schnürch, A. (2023). Oral drug delivery: Influence of mucus on cellular interactions and uptake of lipid-based nanocarriers in Caco-2 cells. Acta Biomater., 167, 416-424.
  29. Wibel, R.; Jörgensen, A.M.; Laffleur, F.; Spleis, H.; Claus, V.; Bernkop-Schnürch, A. (2023). Oral delivery of calcitonin-ion pairs: In vivo proof of concept for a highly lipophilic counterion. Int. J. Pharm., 631, 122476.
  30. Zöller, K.; Laffleur, F.; Claus, V.; Knoll, P.; To, D.; Bernkop-Schnürch, A. (2023). Development and in vivo evaluation of nanoemulsions for oral delivery of low molecular weight heparin. J.Drug Del. Sci. Tech., 86, 104686.
  1. Akkuş-Dağdeviren, Z.B.; Fürst, A.; Friedl, J.D.; Tribus, M.; Bernkop-Schnürch, A. (2022). Nanoarchitectonics of Layer-by-Layer (LbL) coated nanostructured lipid carriers (NLCs) for Enzyme-Triggered charge reversal. J. Colloid & Interface Sci., 629(Pt A), 541-553.
  2. Campani, V.; Salaroglio, I.C.; Nele, V.; Kopecka, J.; Bernkop-Schnürch, A.; Riganti, C.; De Rosa, G. (2022). Targeted Self-Emulsifying Drug Delivery Systems to Restore Docetaxel Sensitivity in Resistant Tumors. Pharmaceutics, 14(2), 292.
  3. Efiana, N.A.; Fürst, A.; Saleh, A.; Shahzadi, I.; Bernkop-Schnürch, A. (2022). Phosphate decorated lipid-based nanocarriers providing a prolonged mucosal residence time. Int. J. Pharm., 625, 122096.
  4. Federer, C.; Claus, V.; Hock, N.; Friedl, J.D.; Wibel, R.; Bernkop-Schnürch, A. (2022). Charge-reversal nanoemulsions: A systematic investigation of phosphorylated PEG-based surfactants. Int. J. Pharm., 613, 121438.
  5. Federer, C.; Spleis, H.V.; Summonte, S.; Friedl, J.D.; Wibel, R.; Bernkop-Schnürch, A. (2022). Preparation and Evaluation of Charge Reversal Solid Lipid Nanoparticles. J. Pharm. Sci., 111(8), 2270-2279.
  6. Friedl, D.J.; Wibel, R.; Akkuş-Dağdeviren, Z.B.; Bernkop-Schnürch, A. (2022). Reactive oxygen species (ROS) in colloidal systems: Are "PEG-free" surfactants the answer? J. Colloid & Interface Sci., 616, 571-583.
  7. Friedl, J.D.; Jörgensen, A.M.; Nguyen Le, N.M.; Steinbring, C.; Bernkop-Schnürch, A. (2022). Replacing PEG-surfactants in self-emulsifying drug delivery systems: Surfactants with polyhydroxy head groups for advanced cytosolic drug delivery. Int. J. Pharm., 618, 121633.
  8. Friedl, J.D.; Walther, M.; Vestweber, P.K.; Wächter, J.; Knoll, P.; Jörgensen, A.M.; Bernkop-Schnürch, A.; Windbergs. M. (2022). SEDDS-loaded mucoadhesive fiber patches for advanced oromucosal delivery of poorly soluble drugs. J. Control. Rel., 348, 692-705.
  9. Fürst, A.; Shahzadi, I.; Burcu Akkuş-Dağdeviren, Z.; Kali, G.; Hupfauf, A.; Gust, R.; Bernkop-Schnürch,A. (2022). Entirely S-protected thiolated hydroxyethylcellulose: Design of a dual cross-linking approach for hydrogels. Eur. J. Pharm. Biopharm., 181, 292-299.
  10. Grassiri, B.; Cesari, A.; Balzano, F.; Migone, C.; Kali, G.; Bernkop-Schnürch, A.; Uccello-Barretta, G.; Zambito, Y.; Piras, A.M. (2022). Thiolated 2-Methyl-β-Cyclodextrin as a Mucoadhesive Excipient for Poorly Soluble Drugs: Synthesis and Characterization. Polymers (Basel), 14(15), 3170.
  11. Grassiri, B.; Knoll, P.; Fabiano, A.; Piras, A.M.; Zambito, Y.; Bernkop-Schnürch, A. (2022). Thiolated Hydroxypropyl-β-cyclodextrin: A Potential Multifunctional Excipient for Ocular Drug Delivery. Int. J. Mol. Sci., 23(5), 2612.
  12. Haddadzadegan, S.; Dorkoosh, F.; Bernkop-Schnürch, A. (2022). Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers. Adv. Drug Del. Rev., 182, 114097.
  13. Hock, N.; Racaniello, G.F.; Aspinall, S.; Denora, N.; Khutoryanskiy, V.V.; Bernkop-Schnürch, A. (2022). Thiolated Nanoparticles for Biomedical Applications: Mimicking the Workhorses of Our Body. Adv. Sci. (Weinh), 9(1), e2102451.
  14. Kali, G.; Knoll, P.; Bernkop-Schnürch, A. (2022). Emerging technologies to increase gastrointestinal transit times of drug delivery systems. J. Control. Rel., 346, 289-299.
  15. Kiss, T.; Ambrus, R.; Abdelghafour, M.M.; Zeiringer, S.; Selmani, A.; Roblegg, E.; Budai-Szűcs, M.; Janovák, L.; Lőrinczi, B.; Deák, Á.; Bernkop-Schnürch, A.; Katona, G. (2022). Preparation and detailed characterization of the thiomer chitosan-cysteine as a suitable mucoadhesive excipient for nasal powders. Int. J. Pharm., 626, 122188.
  16. Knoll, P.; Hörmann, N.; Nguyen Le, N.M.; Wibel, R.; Gust, R.; Bernkop-Schnürch, A. (2022). Charge converting nanostructured lipid carriers containing a cell-penetrating peptide for enhanced cellular uptake. J. Colloid & Interface Sci., 628(Pt A), 463-475.
  17. Le, N.N.; Le-Vinh, B.; Friedl, .JD.; Jalil, A.; Kali, G.; Bernkop-Schnürch, A. (2022). Polyaminated pullulan, a new biodegradable and cationic pullulan derivative for mucosal drug delivery. Carbohydr. Polym., 282, 119143.
  18. Le‐Vinh, B.; Akkuş‐Dağdeviren, Z.B.; Le, N.M.N.; Nazir, I.; Bernkop‐Schnürch, (2022). Alkaline Phosphatase: A Reliable Endogenous Partner for Drug Delivery and Diagnostics. Adv. Ther., 2100219.
  19. Nguyen Le, N.M.; Zsák, S.; Le-Vinh, B.; Friedl, J.D.; Kali, G.; Knoll, P.; Seitter, H.W.; Koschak, A., Bernkop-Schnürch, A. (2022). Charge-Converting Nanoemulsions as Promising Retinal Drug and Gene Delivery Systems. ACS Appl. Mater. Interfaces, 14(39), 44981-44991.
  20. Racaniello, G.F.; Knoll, P.; Jörgensen, A.M.; Arduino, I.; Laquintana, V.; Lopedota, A.A.; Bernkop-Schnürch, A.; Denora, N. (2022). Thiolation of non-ionic surfactants for the development of lipid-based mucoadhesive drug delivery systems. Eur. J. Pharm. Biopharm., 179, 95-104.
  21. Saleh, A.; Akkuş-Dağdeviren, Z.B.; Friedl, J.D.; Knoll, P.; Bernkop-Schnürch, A. (2022). Chitosan – Polyphosphate nanoparticles for a targeted drug release at the absorption membrane. Heliyon, 8(9), e10577.
  22. Selmani, A.; Seibert, E.; Tetyczka, C.; Kuehnelt, D.; Vidakovic, I.; Kornmueller, K.; Absenger-Novak, M.; Radatović, B.; Vinković Vrček, I.; Leitinger, G.; Fröhlich, E.; Bernkop-Schnürch, A.; Roblegg, E.; Prassl, R. (2022). Thiolated Chitosan Conjugated Liposomes for Oral Delivery of Selenium Nanoparticles. Pharmaceutics, 14(4), 803.
  23. Veider, F.; Akkuş-Dağdeviren, Z.B.; Knoll, P.; Bernkop-Schnürch, A. (2022). Design of nanostructured lipid carriers and solid lipid nanoparticles for enhanced cellular uptake. Int. J. Pharm., 624, 122014.
  24. Wibel, R.; Knoll, P.; Le-Vinh, B.; Kali, G.; Bernkop-Schnürch, A. (2022). Synthesis and evaluation of sulfosuccinate-based surfactants as counterions for hydrophobic ion pairing. Acta Biomater., 144, 54-66.
  25. Zaichik, A.; Steinbring, C.; Friedl, J.; Bernkop-Schnürch, A. (2022). Development and In Vitro Characterization of Transferrin-Decorated Nanoemulsion Utilizing Hydrophobic Ion Pairing for Targeted Cellular Uptake. J.Pharm. Inn., 17, 690–700.
  26. Zöller, K.; To, D.; Knoll, P.; Bernkop-Schnürch, A. (2022). Digestion of lipid excipients and lipid-based nanocarriers by pancreatic lipase and pancreatin. Eur. J. Pharm. Biopharm., 176, 32-42.
  1. Akkuş-Dağdeviren, Z.B.; Wolf, J.D.; Kurpiers, M.; Shahzadi, I.; Steinbring, C.; Bernkop-Schnürch, A. (2021). Charge reversal self-emulsifying drug delivery systems: A comparative study among various phosphorylated surfactants. J. Colloid & Interface Sci., 589, 532-544. 
  2. Asim, M.H.; Ijaz, M.; Mahmood, A.; Knoll, P.; Jalil, A.; Arshad, S.; Bernkop-Schnürch, A. (2021). Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery. Int. J. Pharm., 599, 120451. 
  3. Dizdarević, A.; Marić, M.; Shahzadi, I.; Ari Efiana, N.; Matuszczak, B.; Bernkop-Schnürch, A. (2021). Imine bond formation as a tool for incorporation of amikacin in self-emulsifying drug delivery systems (SEDDS). Eur. J. Pharm. Biopharm., 162, 82-91. 
  4. Federer, C.; Kurpiers, M.; Bernkop-Schnürch, A. (2021). Thiolated Chitosans: A Multi-talented Class of Polymers for Various Applications. Biomacromolecules, 22, 24-56. 
  5. Friedl, J.D.; Jörgensen, A.M.; Le-Vinh, B.; Braun, D.E.; Tribus, M.; Bernkop-Schnürch, A. (2021). Solidification of self-emulsifying drug delivery systems (SEDDS): Impact on storage stability of a therapeutic protein. J. Colloid & Interface Sci., 584, 684-697. 
  6. Friedl, J.D.; Nele, V.; De Rosa, G.; Bernkop-Schnürch, A. (2021). Bioinert, Stealth or Interactive: How Surface Chemistry of Nanocarriers Determines Their Fate In Vivo. Adv. Funct. Mat., 31, 2103347. 
  7. Grassiri, B.; Zambito, Y.; Bernkop-Schnürch, A. (2021). Strategies to prolong the residence time of drug delivery systems on ocular surface. Adv. Colloid Interf. Sci., 288, 102342. 
  8. Knoll, P.; Le, N.N.; Wibel, R.; Baus, R.A.; Kali, G.; Asim, M.H.; Bernkop-Schnürch, A. (2021). Thiolated pectins: In vitro and ex vivo evaluation of three generations of thiomers. Acta Biomater., 135,139-149. 
  9. Kurpiers, M.; Wolf, J.D.; Spleis, H.; Steinbring, C.; Jörgensen, A.M.; Matuszczak, B.; Bernkop-Schnürch, A. (2021). Lysine-Based Biodegradable Surfactants: Increasing the Lipophilicity of Insulin by Hydrophobic Ion Paring. J. Pharm. Sci., 110, 124-134. 
  10. Lam, H.T.; Le, N.N.; Phan, T.N.Q.; Bernkop-Schnürch, A. (2021). Mucolytic self-emulsifying drug delivery systems (SEDDS) containing a hydrophobic ion-pair of proteinase. Eur. J. Pharm. Sci., 162, 105658. 
  11. Lam, H.T.; Zupancic, O.; Laffleur, F.; Bernkop-Schnürch, A. (2021). Mucoadhesive properties of polyacrylates:Structure – Function relationship. Int. J. Adh. Adhs., 107, 102857. 
  12. Le, N.N.; Steinbring, C.; Le-Vinh, B.; Jalil, A.; Matuszczak, B.; Bernkop-Schnürch, A. (2021). Polyphosphate coatings: A promising strategy to overcome the polycation dilemma. J. Colloid & Interface Sci., 587, 279-289. 
  13. Le-Vinh, B.; Steinbring, C.; Wibel, R.; Friedl, J.D.; Bernkop-Schnürch, A. (2021). Size shifting of solid lipid nanoparticle system triggered by alkaline phosphatase for site specific mucosal drug delivery. Eur. J. Pharm. Biopharm., 163, 109-119. 
  14. Lupo, N.; Steinbring, C.; Friedl, J.D.; Le-Vinh, B.; Bernkop-Schnürch, A. (2021). Impact of Bile Salts and a Medium Chain Fatty Acid on the Physical Properties of Self-Emulsifying Drug Delivery Systems. Drug Dev. Ind. Pharm., 47, 22-35. 
  15. Racaniello, G.F.; Laquintana, V.; Summonte, S.; Lopedota, A.; Cutrignelli, A.; Lopalco, A.; Franco, M.; Bernkop-Schnürch, A.; Denora, N. (2021). Spray-dried mucoadhesive microparticles based on S-protected thiolated hydroxypropyl-β-cyclodextrin for budesonide nasal delivery. Int. J. Pharm., 603, 120728. 
  16. Shahzadi, I.; Fürst, A.; Knoll, P.; Bernkop-Schnürch, A. (2021). Nanostructured Lipid Carriers (NLCs) for Oral Peptide Drug Delivery: About the Impact of Surface Decoration. Pharmaceutics, 13, 1312. 
  17. Sharifi, F.; Jahangiri, M.; Nazir, I.; Asim, M.H.; Ebrahimnejad, P.; Hupfauf, A.; Gust, R.; Bernkop-Schnürch, A. (2021). Zeta potential changing nanoemulsions based on a simple zwitterion. J. Colloid & Interface Sci., 585, 126-137. 
  18. Summonte, S.; Racaniello, G.F.; Lopedota, A.; Denora, N.; Bernkop-Schnürch, A. (2021). Thiolated polymeric hydrogels for biomedical application: Cross-linking mechanisms. J. Control. Rel., 330, 470-482. 
  19. Uhl, P.; Sauter, M.; Hertlein, T.; Witzigmann, D.; Laffleur, F.; Hofhaus, G.; Fidelj, V.; Tursch, A.; Özbek, S.; Hopke, E.; Haberkorn, U.; Bernkop-Schnürch, A.; Ohlsen, K.; Fricker, G.; Mier, W. (2021). Overcoming the Mucosal Barrier: Tetraether Lipid-Stabilized Liposomal Nanocarriers Decorated with Cell-Penetrating Peptides Enable Oral Delivery of Vancomycin. Adv. Ther., 4, 2000247. 
  20. Vinarov, Z.; Abrahamsson, B.; Artursson, P.; Batchelor, H.; Berben, P.; Bernkop-Schnürch, A.; Butler, J.; Ceulemans, J.; Davies, N.; Dupont, D.; Flaten, G.E.; Fotaki, N.; Griffin, B.T.; Jannin, V.; Keemink, J.; Kesisoglou, F.; Koziolek, M.; Kuentz, M.; Mackie, A.; Meléndez-Martínez, A.J.; McAllister, M.; Müllertz, A.; O'Driscoll, C.M.; Parrott, N.; Paszkowska, J.; Pavek, P.; Porter, C.J.H.; Reppas, C.; Stillhart, C.; Sugano, K.; Toader, E.; Valentová, K.; Vertzoni, M.; De Wildt, S.N.; Wilson, C.G.; Augustijns, P. (2021). Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network. Adv. Drug Del. Rev., 171, 289-331. 
  21. Wibel, R.; Braun, D.E.; Hämmerle, L.; Jörgensen, A.M.; Knoll, P.; Salvenmoser, W.; Steinbring, C.; Bernkop-Schnürch, A. (2021). In Vitro Investigation of Thiolated Chitosan Derivatives as Mucoadhesive Coating Materials for Solid Lipid Nanoparticles. Biomacromolecules, 22, 3980-3991. 
  22. Yaqoob, M.; Jalil, A.; Bernkop-Schnürch, A. (2021). Mucoadhesive Polymers: Gateway to Innovative Drug Delivery. Mod. Contr. Drug Del. Syst. 2021, 351-383.
  1. Arshad, S.; Rehman, M.U.; Hussain, A.M.; Nazir, I.; Shahzadi, I.; Mousli, M.; Bernkop-Schnürch, A. (2020). S-Protected thiolated nanostructured lipid carriers exhibiting improved mucoadhesive properties. Int. J. Pharm., 587, 119690.
  2. Asim, M.H.; Nazir, I.; Jalil, A.; Laffleur, F.; Matuszczak, B.; Bernkop-Schnürch, A. (2020). Per-6-Thiolated Cyclodextrins: A Novel Type of Permeation Enhancing Excipients for BCS Class IV Drugs. ACS Appl. Mater. Interfaces, 12(7), 7942-7950.
  3. Asim, M.H.; Silberhumer, S.; Shahzadi, I.; Jalil, A.; Matuszczak, B.; Bernkop-Schnürch, A. (2020). S-protected thiolated hyaluronic acid: In-situ crosslinking hydrogels for 3D cell culture scaffold. Carbohydr. Polym., 237, 116092.
  4. Baus, R.A.; Leichner, C.; Steinbring, C.; Bernkop-Schnürch, A. (2020). Strategies for improved hair binding: Keratin fractions and the impact of cationic substructures. Int. J. Biol. Macromol., 160, 201-211.
  5. Etezadi, H.; Maleki, A.; Friedl, J.D.; Bernkop-Schnürch, A. (2020). Storage stability of proteins in a liquid-based formulation: Liquid vs. solid self-emulsifying drug delivery. Int. J. Pharm., 590, 119918.
  6. Friedl, J.D.; Steinbring, C.; Zaichik, S.; Le, N.N.; Bernkop-Schnürch, A. (2020). Cellular uptake of self-emulsifying drug-delivery systems: polyethylene glycol versus polyglycerol surface. Nanomedicine (Lond), 15(19), 1829-1841.XXXXXXX
  7. Hussain, A.M.; Nazir, I.; Jalil, A.; Matuszczak, B.; Bernkop-Schnürch, A. (2020). Tetradeca-thiolated cyclodextrins: Highly mucoadhesive and in-situ gelling oligomers with prolonged mucosal adhesion. Int. J. Pharm., 577, 119040.
  8. Ismail, R.; Phan, T.N.Q.; Laffleur, F.; Csóka, I.; Bernkop-Schnürch, A. (2020). Hydrophobic ion pairing of a GLP-1 analogue for incorporating into lipid nanocarriers designed for oral delivery. Eur. J. Pharm. Biopharm., 152, 10-17.
  9. Jalil, A.; Asim, M.H.; Nazir, I.; Matuszczak, B.; Bernkop-Schnürch, A. (2020). Self-emulsifying drug delivery systems containing hydrophobic ion pairs of polymyxin B and agaric acid: A decisive strategy for enhanced antimicrobial activity J. Mol. Liquids, 311, 113298.
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  14. Le, N.N.; Steinbring, C.; Matuszczak, B.; Baus, .RA.; Tribus, M.; Pham, T.; Bechtold, T.; Bernkop-Schnürch, A. (2020). Grafting of wool fibers through disulfide bonds: An advanced application of S-protected thiolated starch. Int. J. Biol. Macromol., 147, 473-481.
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  19. Netsomboon, K.; Jalil, A.; Laffleur, F.; Hupfauf, A.; Gust, R.; Bernkop-Schnürch, A. (2020). Thiolated chitosans: Are Cys-Cys ligands key to the next generation? Carbohydr. Polym., 242, 116395.
  20. Nouri, A.; Jelkmann, M.; Khoee, S.; Bernkop-Schnürch, A. (2020). Diaminated Starch: A Competitor of Chitosan with Highly Mucoadhesive Properties due to Increased Local Cationic Charge Density. Biomacromolecules, 21(2), 999-1008.
  21. Prüfert, F.; Fischer, F.; Leichner, C.; Zaichik, S.; Bernkop-Schnürch, A. (2020). Development and In Vitro Evaluation of Stearic Acid Phosphotyrosine Amide as New Excipient for Zeta Potential Changing Self-Emulsifying Drug Delivery Systems. Pharm. Res., 37(4), 79.
  22. Prüfert, F.; Hering, U.; Zaichik, S.; Le, N.N.; Bernkop-Schnürch, A. (2020). Synthesis and in vitro characterization of a preactivated thiolated acrylic acid/acrylamide-methylpropane sulfonic acid copolymer as a mucoadhesive sprayable polymer. Int. J. Pharm., 583, 119371.
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  1. Akkus, Z.B.; Nazir, I.; Jalil, A.; Tribus, M.; Bernkop-Schnürch, A. (2019). Zeta Potential Changing Polyphosphate Nanoparticles: A promising approach to overcome the mucus and epithelial barrier. Pharm., 16, 2817-2825.
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  1. Afzal, S.; Khan, S.; Ranjha, N.M.; Jalil, A.; Riaz, A.; Haider, M.S.; Sarwar, S.; Saher, F.; Naeem, F. (2018). The Structural, Crystallinity, and Thermal Properties of pH-responsive Interpenetrating Gelatin/Sodium Alginate-based Polymeric Composites for the Controlled Delivery of Cetirizine HCl. Turk. J. Pharm. Sci., 15(1), 63-76.
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  1. Albrecht-Schgoer, K.; Barthelmes, J.; Schgoer, W.; Theurl, M.; Nardin, I.; Lener, D.; Gutmann, C.; Dünnhaupt, S.; Bernkop-Schnürch, A.; Kirchmair, R. (2017). Nanoparticular delivery system for a secretoneurin derivative induces angiogenesis in a hind limb ischemia model. J. Control. Rel., 250, 1-8.
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  9. Ijaz, M.; Prantl, M.; Lupo, N.; Laffleur, F.; Hussain Asim, M.; Matuszczak, B.; Bernkop-Schnürch, A. (2017). Development of pre-activated α-cyclodextrin as a mucoadhesive excipient for intra-vesical drug delivery. Int J Pharm., 534, 339-347.
  10. Köllner, S.; Nardin, I.; Markt, R.; Griesser, J.; Prüfert, F.; Bernkop-Schnürch, A. (2017). Self-emulsifying drug delivery systems: Design of a novel vaginal delivery system for curcumin. Eur. J. Pharm. Biopharm., 115, 268-275.
  11. Laffleur, F.; Bernkop-Schnürch, A. (2017). Evaluation of peptide drug delivery via skin barrier-impact of permeation enhancers. J. Drug Del. Sci.Tech., 41, 191-196.
  12. Laffleur, F.; Knapp, K.; Suchaoin, W.; Partenhauser, A.; Netsomboon, K.; Bernkop-Schnürch, A. (2017). Comparison of mucoadhesive and cohesive features of poly(acrylic acid)-conjugates respective their molecular mass. Eur. J. Pharm. Biopharm., 113, 149-156.
  13. Laffleur, F.; Netsomboon, K.; Bernkop-Schnürch, A.; Westmeier, D.; Stauber, R.H.; Docter, D. (2017). Comprehensive mucoadhesive study of anionic polymers and their derivate. European Polymer Journal, 93, 314-322
  14. Lam, H.T.; Leonaviciute, G.; Zupančič, O.; Bernkop-Schnürch, A. (2017). Thiomers: Impact of in situ cross-linkers on mucoadhesive properties. Eur. J. Pharm. Sci., 106, 41-48.
  15. Leichner, C.; Menzel, C.; Laffleur, F.; Bernkop-Schnürch, A. (2017). Development and in vitro characterization of a papain loaded mucolytic self-emulsifying drug delivery system (SEDDS). Int. J. Pharm., 530, 346-353.
  16. Leonaviciute, G.; Adamovic, N.T.; Lam, H.T.; Rohrer, J.; Partenhauser, A.; Bernkop-Schnürch, A. (2017). Self-emulsifying drug delivery systems (SEDDS): Proof-of-concept how to make them mucoadhesive. Eur. J. Pharm. Biopharm., 112, 51-57.
  17. Lupo, N.; Fidahic, U.; Hetényi, G.; Griesser, J.; Bernkop-Schnürch, A. (2017). Inhibitory effect of emulsifiers in sedds on protease activity: Just an illusion? Int. J. Pharm., 526, 23-30.
  18. Lupo, N.; Fodor, B.; Muhammad, I.; Yaqoob, M.; Matuszczak, B.; Bernkop-Schnürch, A. (2017). Entirely S-protected chitosan: A promising mucoadhesive excipient for metronidazole vaginal tablets. Acta Biomater., 64, 106-115.
  19. Maestri, C.A.; Abrami, M.; Hazan, S.; Chistè, E.; Golan, Y.; Rohrer, J.; Bernkop-Schnürch, A.; Grassi, M.; Scarpa, M.; Bettotti, P. (2017). Role of sonication pre-treatment and cation valence in the sol-gel transition of nano-cellulose suspensions. Sci. Rep., 11, 7(1) 11129.
  20. Mahmood, A.; Laffleur, F.; Leonaviciute, G.; Bernkop-Schnürch, A. (2017). Protease-functionalized mucus penetrating microparticles: In-vivo evidence for their potential. Int. J. Pharm., 532, 177-184.
  21. Mahmood, A.; Lanthaler, M.; Laffleur, F.; Huck, C.W.; Bernkop-Schnürch, A. (2017). Thiolated chitosan micelles: Highly mucoadhesive drug carriers. Carbohydr. Polym., 167, 250-258.
  22. Menzel, C.; Jelkmann, M.; Laffleur, F.; Bernkop-Schnürch, A. (2017). Nasal drug delivery: Design of a novel mucoadhesive and in situ gelling polymer. Int. J. Pharm., 517, 196-202.
  23. Netsomboon, K.; Suchaoin, W.; Laffleur, F.; Prüfert, F.; Bernkop-Schnürch, A. (2017). Multifunctional adhesive polymers: Preactivated thiolated chitosan-EDTA conjugates. Eur. J. Pharm. Biopharm., 111, 26-32.
  24. Partenhauser, A.; Netsomboon, K.; Pereira de Sousa, I.; Laffleur, F.; Bernkop-Schnürch, A. (2017). Preactivated silicone oil as potential long-term vitreous replacement with nonemulsifying properties. J. Biomed. Mater. Res. B Appl. Biomater., 105(3), 551-559.
  25. Perrone, M.; Lopalco, A.; Lopedota, A.; Cutrignelli, A.; Laquintana, V.; Douglas, J.; Franco, M.; Liberati, E.; Russo, V.; Tongiani, S.; Denora, N.; Bernkop-Schnürch, A. (2017). Preactivated thiolated glycogen as mucoadhesive polymer for drug delivery. Eur. J. Pharm. Biopharm., 119, 161-169.
  26. Perrone, M.; Lopedota, A.; Liberati, E.; Russo, V.; Cutrignelli, A.; Laquintana, V.; de Sousa, I.P.; Franco, M.; Tongiani, S.; Denora, N.; Bernkop-Schnürch, A. (2017). Natural dendrimers: Synthesis and in vitro characterization of glycogen-cysteamine conjugates. Eur. J. Pharm. Biopharm., 115, 168-176.
  27. Prüfert, F.; Bonengel, S.; Köllner, S.; Griesser, J.; Wilcox, M.D.; Chater, P.I.; Pearson, J.P.; Bernkop-Schnürch, A. (2017). ζ potential changing nanoparticles as cystic fibrosis transmembrane conductance regulator gene delivery system: an in vitro evaluation. Nanomedicine (Lond)., 12(22), 2713-2724.
  28. Prüfert, F.; Bonengel, S.; Menzel, C.; Bernkop-Schnürch, A. (2017). Enhancing the efficiency of thiomers: Utilizing a highly mucoadhesive polymer as backbone for thiolation and preactivation. Eur. J. Pharm. Sci., 96, 309-315.
  29. Rohrer, J.; Partenhauser, A.; Zupančič, O.; Leonavičiūtė, G.; Podričnik, S.; Bernkop-Schnürch, A. (2017). Thiolated gelatin films: Renaissance of gelatin as sustained intraoral dosage form. European Polymer Journal, 87, 48-59.
  30. Suchaoin, W.; Bernkop-Schnürch, A. (2017). Nanocarriers protecting toward an intestinal pre-uptake metabolism. Nanomedicine (Lond)., 12(3), 255-269.
  31. Suchaoin, W.; Mahmood, A.; Netsomboon, K.; Bernkop-Schnürch, A. (2017). Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency. Nanomedicine (Lond)., 12(9), 963-975.
  32. Zupančič, O.; Bernkop-Schnürch, A. (2017). Lipophilic peptide character - What oral barriers fear the most. J. Control. Rel., 255, 242-257.
  33. Zupančič, O.; Grießinger, J.A.; Lam, H.T.; Bernkop-Schnürch, A. (2017). Storage Stability of Bivalirudin: Hydrophilic Versus Lipophilic Solutions. J. Pharm. Sci., 106(5), 1322-1330.
  34. Zupančič, O.; Rohrer, J.; Thanh Lam, H.; Grießinger, J.A.; Bernkop-Schnürch, A. (2017). Development and in vitro characterization of self-emulsifying drug delivery system (SEDDS) for oral opioid peptide delivery. Drug Dev. Ind. Pharm., 43(10), 1694-1702.
  1. Bonengel, S.; Jelkmann, M.; Oh, S.; Mahmood, A.; Ijaz, M.; Bernkop-Schnürch, A. (2016). Charge changing phosphorylated polymers: Proof of in situ mucoadhesive properties. J. Pharm. Biopharm., 105, 203-208.
  2. Bonengel, S.; Prüfert, F.; Jelkmann, M.; Bernkop-Schnürch, A. (2016). Zeta potential changing phosphorylated nanocomplexes for pDNA delivery. Int. J. Pharm., 504, 117-124.
  3. Deutel, B.; Laffleur, F.; Palmberger, T.; Saxer, A.; Thaler, M.; Bernkop-Schnürch, A. (2016). In vitro characterization of insulin containing thiomeric microparticles as nasal drug delivery system. J. Pharm. Sci., 81, 157-161.
  4. Deutel, B.; Laffleur, F.; Thaurer, M.; Thaler, M.; Bernkop-Schnürch, A. (2016). Assembly and in vitro characterization of thiomeric nanoparticles. Drug Dev. Ind. , 42, 730-736.
  5. Grieβinger, J.A.; Hauptstein, S.; Laffleur, F.; Netsomboon, K.; Bernkop-Schnürch, A. (2016). Evaluation of the impact of multivalent metal ions on the permeation behavior of Dolutegravir sodium. Drug Dev. Ind. Pharm., 42, 1118-1126.
  6. Ijaz, M.; Ahmad, M.; Akhtar, N.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Thiolated α-Cyclodextrin: The Invisible Choice to Prolong Ocular Drug Residence Time. J. Pharm. , 105, 2848-2854.
  7. Ijaz, M.; Bonengel, S.; Zupančič, O.; Yaqoob, M.; Hartl, M.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A. (2016). Development of oral self nano-emulsifying delivery system(s) of lanreotide with improved stability against presystemic thiol-disulfide exchange reactions. Expert Opin. Drug Deliv., 13, 923-929.
  8. Ijaz, M.; Griessinger, J.A.; Mahmood, A.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Thiolated Cyclodextrin: Development of a Mucoadhesive Vaginal Delivery System for Acyclovir. Pharm. Sci., 105, 1714-1720.
  9. Laffleur, F. (2016). Mucoadhesive therapeutic compositions: a patent review (2011-2014). Expert Opin Ther Pat., 26(3), 377-388.
  10. Laffleur, F.; Bacher, L.; Netsomboon, K. (2016). Design, characterization and in vitro evaluation of a novel thiolated polymer: preactivated carboxymethyl cellulose. Deliv., 7(1),7-14.
  11. Laffleur, F.; Bacher, L.; Vanicek, S.; Menzel, C.; Muhammad, I. (2016). Next generation of buccadhesive excipient: Preactivated carboxymethyl cellulose. Int J Pharm., 500, 120-127.
  12. Laffleur, F.; Leder, N., Barthelmes, J. (2016). In vitro evaluation of thio-poly acrylic acid for intraoral delivery. Drug Deliv., 23(6), 2065-2073.
  13. Laffleur, F.; Messirek, A. (2016). Development of mucoadhesive thio-carboxymethyl cellulose for application in buccal delivery of drugs. Ther Deliv., 7(2), 63-71.
  14. Laffleur, F.; Michalek, M.; Suchaoin, W.; Ija,z M. (2016). Design and evaluation of buccal-adhesive system made of modified xanthan. Ther Deliv., 7(7):423-429.
  15. Laffleur, F.; Zilio, M.; Menzel, C.; Lupo, N.; Schmutzler, M. (2016). Design, modification and in vitro evaluation of pectin's bucco-adhesiveness. Ther Deliv., 7(6),369-375.
  16. Laffleur, F.; Zilio, M.; Shuwisitkul, D. (2016). Modified biomolecule as potential vehicle for buccal delivery of doxepin. Ther Deliv. 2016 Oct;7(10):683-689.
  17. Leonaviciute, G.; Bonengel, S.; Mahmood, A.; Ahmad Idrees, M.; Bernkop-Schnürch, A. (2016). S-protected thiolated hydroxyethyl cellulose (HEC): Novel mucoadhesive excipient with improved stability. Polym., 144, 514-521.
  18. Leonaviciute, G.; Suchaoin, W.; Matuszczak, B.; Lam, HT.; Mahmood, A.; Bernkop-Schnürch, A. (2016). Preactivated thiolated pullulan as a versatile excipient for mucosal drug targeting. Polym., 151, 743-751.
  19. Leonaviciute, G.; Zupančič, O.; Prüfert, F.; Rohrer, J.; Bernkop-Schnürch, A. (2016). Impact of lipases on the protective effect of SEDDS for incorporated peptide drugs towards intestinal peptidases. J. Pharm., 508, 102-108.
  20. Mahmood, A.; Bonengel, S.; Laffleur, F.; Ijaz, M.; Idrees, M.A.; Hussain, S.; Huck, C.W.; Matuszczak, B.; Bernkop-Schnürch, A. (2016). Can thiolation render a low molecular weight polymer of just 20-kDa mucoadhesive? Drug Dev. Ind. Pharm., 42, 686-693.
  21. Mahmood, A.; Prüfert, F.; Efiana, N.A.; Ashraf, M.I.; Hermann, M.; Hussain, S.; Bernkop-Schnürch, A. (2016). Cell-penetrating self-nanoemulsifying drug delivery systems (SNEDDS) for oral gene delivery. Expert Opin. Drug Deliv., 13, 1503-1512.
  22. Menzel, C.; Bonengel, S.; de Sousa, I.; Laffleur, F.; Prüfert, F.; Bernkop-Schnürch, A. (2016). Preactivated Thiolated Nanoparticles: A Novel Mucoadhesive Dosage Form. Int. J. Pharm., 497, 123-128.
  23. Menzel, C.; Silbernagl, J.; Laffleur, F.; Leichner, C.; Jelkmann, M.; Huck, C.W.; Hussain, S.; Bernkop-Schnürch, A. (2016). 2,2'Dithiodinicotinyl ligands: Key to more reactive thiomers. Int. J. Pharm., 503, 199-206.
  24. Netsomboon, K.; Bernkop-Schnürch, A. (2016). Mucoadhesive vs. mucopenetrating particulate drug delivery. J. Pharm. Biopharm., 98, 76-89.
  25. Netsomboon, K.; Feßler, A.; Erletz, L.; Prüfert, F.; Ruetz, M.; Kieninger, C.; Kräutler, B.; Bernkop-Schnürch, A. (2016). Vitamin B12 and derivatives-In vitro permeation studies across Caco-2 cell monolayers and freshly excised rat intestinal mucosa. J. Pharm., 497, 129-135.
  26. Netsomboon, K.; Laffleur, F.; Bernkop-Schnürch, A. (2016). P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer. Drug Dev. Ind. Pharm., 42, 668-675.0
  27. Netsomboon, K.; Laffleur, F.; Suchaoin, W.; Bernkop-Schnürch, A. (2016). Novel in vitro transport method for screening the reversibility of P-glycoprotein inhibitors. J. Pharm. Biopharm., 100, 9-14.
  28. Netsomboon, K.; Partenhauser, A.; Rohrer, J.; Sündermann, N.; Prüfert, F.; Suchaoin, W.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Preactivated thiomers for intranasal delivery of apomorphine: in vitro and in vivo evaluation. J. Pharm. Biopharm., 109, 35-42.
  29. Partenhauser, A.; Bernkop-Schnürch, A. (2016). Mucoadhesive polymers in the treatment of dry X syndrome. Drug Discovery Today, 21, 1051-1062.
  30. Partenhauser, A.; Netsomboon, K.; Leonaviciute, G.; Bernkop-Schnürch, A. (2016). Evaluation of thiolated silicone oil as advanced mucoadhesive antifoaming agent. Drug Deliv., 23, 2711-2719.
  31. Partenhauser, A.; Zupancic, O.; Podricnik, S.; Rohrer, J.; Leichner, C.; Bernkop-Schnürch, A. (2016). Entirely S-protected silicone oil as second generation mucoadhesive agent. European Polymer Journal 76, 53-62.
  32. Partenhauser, A.; Zupančič, O.; Rohrer, J.; Bonengel, S.; Bernkop-Schnürch, A. (2016). Thiolated silicone oils as adhesive skin protectants for improved barrier function. J. Cosmet.Sci. 38(3), 257-265
  33. Pereira de Sousa, I.; Buttenhauser, K.; Suchaoin, W.; Partenhauser, A.; Perrone, M.; Matuszczak, B.; Bernkop-Schnürch, A. (2016). Thiolated graphene oxide as promising mucoadhesive carrier for hydrophobic drugs. J. Pharm., 509, 360-367.
  34. Pereira de Sousa, I.; Moser, T.; Steiner, C.; Fichtl, B.; Bernkop-Schnürch, A. (2016). Insulin loaded mucus permeating nanoparticles: Addressing the surface characteristics as feature to improve mucus permeation. J. Pharm., 500, 236-244.
  35. Pereira de Sousa, I.; Suchaoin, W.; Zupančič, O.; Leichner, C.; Bernkop-Schnürch, A. (2016). Totally S-protected hyaluronic acid: Evaluation of stability and mucoadhesive properties as liquid dosage form. Polym., 152, 632-638.
  36. Rohrer, J.; Partenhauser, A.; Hauptstein, S.; Gallati, C.; Matuszczak, B.; Abdulkarim, M.; Gunbleton, M.; Bernkop-Schnürch, A. (2016). Mucus permeating thiolated self-emusifying drug derlivery systems. Eur. J. Pharm. , 98, 90-97.
  37. Sakloetsakun, D.; Preechagoon, D.; Bernkop-Schnürch, A.; Pongjanyakul, T. (2016). Chitosan-gum arabic polyelectrolyte complex films: physicochemical, mechanical and mucoadhesive properties. Dev. Technol., 21, 590-599.
  38. Suchaoin, W.; Bonengel, S.; Grießinger, J.A.; Pereira de Sousa, I.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A. (2016). Novel bioadhesive polymers as intra-articular agents: Chondroitin sulfate-cysteine conjugates. J. Pharm. Biopharm., 101, 25-32.
  39. Suchaoin, W.; Pereira de Sousa, I.; Netsomboon, K.; Lam, H.T.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Development and in vitro evaluation of zeta potential changing self-emulsifying drug delivery systems for enhanced mucus permeation. J. Pharm., 510, 255-262.
  40. Suchaoin, W.; Pereira de Sousa, I.; Netsomboon, K.; Rohrer, J.; Hoffmann Abad, P.; Laffleur, F.; Matuszczak, B.; Bernkop-Schnürch, A. (2016). Mucoadhesive polymers: Synthesis and in vitro characterization of thiolated poly(vinyl alcohol). J. Pharm., 503, 141-149.
  41. Zupančič, O.; Grießinger, J.A.; Rohrer, J.; Pereira de Sousa, I.; Danninger, L.; Partenhauser, A.; Sündermann, N.E.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Development, in vitro and in vivo evaluation of a self-emulsifying drug delivery system (SEDDS) for oral enoxaparin administration. J. Pharm. Biopharm., 109, 113-121.
  42. Zupančič, O.; Leonaviciute, G.; Lam, H.T.; Partenhauser, A.; Podričnik, S.; Bernkop-Schnürch, A. (2016). Development and in vitro evaluation of an oral SEDDS for desmopressin. Drug Deliv., 23, 2074-2083.
  43. Zupančič, O.; Partenhauser, A.; Lam, H.T.; Rohrer, J.; Bernkop-Schnürch, A. (2016). Development and in vitro characterisation of an oral self-emulsifying delivery system for daptomycin. J. Pharm. Sci., 81, 129-136.
  1. Abdulkarim, M.; Agulló, N.; Cattoz, B.; Griffiths, P.; Bernkop-Schnürch, A.; Borros, S.G.; Gumbleton, M. (2015). Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogeneity across polyelectrolyte, pegylated and viral particles. J. Pharm. Biopharm., 97(Pt A), 230-238.
  2. Ay Şenyiğit, Z.; Karavana, S.Y.; İlem-Özdemir, D.; Çalışkan, Ç.; Waldner, C.; Şen, S.; Bernkop-Schnürch, A.; Baloğlu, E. (2015). Design and evaluation of an intravesical delivery system for superficial bladder cancer: preparation of gemcitabine HCl-loaded chitosan–thioglycolic acid nanoparticles and comparison of chitosan/poloxamer gels as carriers J. Nanomedicine, 10, 6493-6507.
  3. Bonengel, S.; Hauptstein, S.; Leonaviciute, G.; Griessinger, J.; Bernkop-Schnürch, A. (2015). Thiolated alkyl-modified carbomers: Novel excipients for mucoadhesive emulsions. J. Pharm. Sci., 75, 123-130.
  4. Bonengel, S.; Prüfert, F.; Perera, G.; Schauer, J.; Bernkop-Schnürch, A. (2015). Polyethylene imine-6-phosphogluconic acid nanoparticles--a novel zeta potential changing system. J. Pharm., 483, 19-25.
  5. Dünnhaupt, S.; Barthelmes, J.; Köllner, S.; Sakloetsakun, D.; Shahnaz, G.; Düregger, A.; Bernkop-Schnürch, A. (2015). Thiolated nanocarriers for oral delivery of hydrophilic macromolecular drugs. Polym., 117, 577-584.
  6. Dünnhaupt, S.; Kammona, O.; Waldner, C.; Kiparissides, C.; Bernkop-Schnürch, A. (2015). Nano-carrier systems: Strategies to overcome the mucus gel barrier. J. Pharm. Biopharm., 96, 447-453.
  7. Grabovac, V.; Laffleur, F.; Bernkop-Schnürch, A. (2015). Thiomers: Influence of molecular mass and thiol group content of poly(acrylic acid) on efflux pump inhibition. J. Pharm., 493, 374-379.
  8. Grießinger, J.; Dünnhaupt, S.; Cattoz, B.; Griffiths, P.; Oh, S.; Gómez, S.B.; Wilcox, M.; Pearson, J.; Gumbleton, M.; Abdulkarim, M.; Pereira de Sousa, I.; Bernkop-Schnürch, A. (2015). Methods to determine the interactions of micro- and nanoparticles with mucus. J. Pharm. Biopharm., 96, 464-476.
  9. Hauptstein, S.; Dezorzi, S.; Prüfert, F.; Matuszczak, B.; Bernkop-Schnürch, A. (2015). Synthesis and in vitro characterization of a novel S-protected thiolated alginate. Polym., 124, 1-7.
  10. Hauptstein, S.; Prüfert, F.; Bernkop-Schnürch, A. (2015). Self-nanoemulsifying drug delivery systems as novel approach for pDNA drug delivery. J. Pharm., 487, 25-31.
  11. Hebar, A.; Koller, C.; Seifert, J.M.; Chabicovsky, M.; Bodenteich, A.; Bernkop-Schnürch, A.; Grassauer, A.; Prieschl-Grassauer, E. (2015). Non-clinical safety evaluation of intranasal iota-carrageenan. PLoS One. 10, e0122911.
  12. Ijaz, M.; Bernkop-Schnürch, A. (2015). Preactivated thiomers: their role in drug delivery. Expert Opin. Drug Deliv., 12, 1269-1281.
  13. Ijaz, M.; Matuszczak, B.; Rahmat, D.; Mahmood, A.; Bonengel, S.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A. (2015). Synthesis and characterization of thiolated β-cyclodextrin as a novel mucoadhesive excipient for intra-oral drug delivery. Polym., 132, 187-195.
  14. Köllner, S.; Dünnhaupt, S.; Waldner, C.; Hauptstein, S.; Pereira de Sousa, I.; Bernkop-Schnürch, A. (2015). Mucus permeating thiomer nanoparticles. J. Pharm. Biopharm., 97(Pt A), 265-272.
  15. Laffleur, F.; Dachs, S. (2015). Development of novel mucoadhesive hyaluronic acid derivate as lubricant for the treatment of dry eye syndrome. Deliv., 6(10), 1211-1219.
  16. Laffleur, F.; Fischer, A.; Schmutzler, M.; Hintzen, F.; Bernkop-Schnürch, A. (2015). Evaluation of functional characteristics of preactivated thiolated chitosan as potential therapeutic agent for dry mouth syndrome. Acta Biomater., 21, 123-131.
  17. Laffleur, F.; Psenner, J.; Suchaoin, W. (2015). Permeation enhancement via thiolation: in vitro and ex vivo evaluation of hyaluronic acid-cysteine ethyl ester. Pharm. Sci., 104, 2153-2160.
  18. Laffleur, F.; Psenner, J.; Suchaoin, W. (2015). Permeation enhancement via thiolation: in vitro and ex vivo evaluation of hyaluronic acid-cysteine ethyl ester. Pharm. Sci., 104(7), 2153-2160.
  19. Laffleur, F.; Wagner, J.; Barthelmes, J. (2015). A potential tailor-made hyaluronic acid buccal delivery system comprising rotigotine for Parkinson's disease? Future Med. Chem. 7(10), 1225-1232.
  20. Laffleur, F.; Wagner, J.; Mahmood, A. (2015). In vitro and ex vivo evaluation of biomaterials' distinctive properties as a result of thiolation. Future Med. Chem., 7(4), 449-457.
  21. Leonaviciute, G.; Bernkop-Schnürch, A. (2015). Self-emulsifying drug delivery systems in oral (poly)peptide drug delivery. Expert Opin. Drug Deliv., 12, 1703-1716.
  22. Mahjub, R.; Dorkoosh, F.A.; Rafiee-Tehrani, M.; Bernkop-Schnürch, A. (2015). Oral self-nanoemulsifying peptide drug delivery systems: impact of lipase on drug release. Microencap., 32, 401-407.
  23. Mahmood, A.; Bonengel, S.; Laffleur, F.; Ijaz, M.; Leonaviciute, G.; Bernkop-Schnürch, A. (2015). An in-vitro exploration of permeation enhancement by novel polysulfonate thiomers. J. Pharm., 496, 304-313.
  24. Palmberger, T.F.; Laffleur, F.; Greindl, M.; Bernkop-Schnürch, A. (2015). In vivo evaluation of anionic thiolated polymers as oral delivery systems for efflux pump inhibition. J. Pharm., 491, 318-322.
  25. Partenhauser, A.; Laffleur, F.; Rohrer, J.; Bernkop-Schnürch, A. (2015). Thiolated silicone oil: synthesis, gelling and mucoadhesive properties. Acta Biomater., 16, 169-177.
  26. Pereira de Sousa, I.; Cattoz, B.; Wilcox, M.D.; Griffiths, P.C.; Dalgliesh, R.; Rogers, S.; Bernkop-Schnürch, A. (2015). Nanoparticles decorated with proteolytic enzymes, a promising strategy to overcome the mucus barrier. J. Pharm. Biopharm., 97(Pt A), 257-264.
  27. Pereira de Sousa, I.; Steiner, C.; Schmutzler, M.; Wilcox, M.D.; Veldhuis, J.; Pearson, J.P.; Huck, C.W.; Salvenmoser, W.; Bernkop-Schnürch, A. (2015). Mucus permeating carriers: formulation and characterization of highly densely charged nanoparticles. J. Pharm. Biopharm., 97(Pt A), 273-279.
  28. Perera, G.; Zipser, M.; Bonengel, S.; Salvenmoser, W.; Bernkop-Schnürch, A. (2015). Development of phosphorylated nanoparticles as zeta potential inverting systems. J. Pharm. Biopharm., 97(Pt A), 250-256.
  29. Rohrer, J.; Zupancic, O.; Suchaoin, W.; Netsoomboon, K.; Laffleur, F.; Oh, S.; Bernkop-Schnürch, A. (2015). Synthesis and in vitro characterization of preactivated thiolated gelatin. European Polymer Journal 73, 268–277.
  30. Suchaoin, W.; Bonengel, S.; Hussain, S.; Huck, C.W.; Ma, B.N.; Bernkop-Schnürch, A. (2015). Synthesis and In Vitro Evaluation of Thiolated Carrageenan. Pharm. Sci., 104, 2523-2530.
  1. Bonengel, S.; Bernkop-Schnürch, A. (2014). Thiomers - From bench to market. Control. Rel., 195, 120-129.
  2. Bonengel, S.; Hauptstein, S.; Perera, G.; Bernkop-Schnürch, A. (2014). Thiolated and S-protected hydrophobically modified cross-linked poly(acrylic acid) - A new generation of multifunctional polymers. J. Pharm. Biopharm., 88, 390-396.
  3. Hauptstein, S.; Bonengel, S.; Griessinger, J.; Bernkop-Schnürch, A. (2014). Synthesis and characterization of pH tolerant and mucoadhesive (thiol-polyethylene glycol) chitosan graft polymer for drug delivery. Pharm. Sci., 103, 594-601.
  4. Hauptstein, S.; Bonengel, S.; Rohrer, J.; Bernkop-Schnürch, A. (2014). Preactivated thiolated poly(methacrylic acid-co-ethyl acrylate): Synthesis and evaluation of mucoadhesive potential. J. Pharm. Sci., 63, 132-139.
  5. Hauptstein, S.; Hintzen, F.; Müller, C.; Ohm, M.; Bernkop-Schnürch, A. (2014). Development and in vitro evaluation of a buccal drug delivery system based on preactivated thiolated pectin. Drug Dev. Ind. Pharm., 40, 1530-1537.
  6. Hintzen, F.; Perera, G.; Hauptstein, S.; Müller, C.; Laffleur, F.; Bernkop-Schnürch, A. (2014). In vivo evaluation of an oral self-microemulsifying drug delivery system (SMEDDS) for leuprorelin. J. Pharm., 472, 20-26.
  7. Laffleur, F.; Hintzen, F.; Shahnaz, G.; Rahmat, D.; Leithner, K.; Bernkop-Schnürch, A. (2014). Development and in vitro evaluation of slippery nanoparticles for enhanced diffusion through native mucus. Nanomedicine, 9, 387-396.
  8. Laffleur, F.; Röggla, J.; Idrees, M.A.; Griessinger, J. (2014). Chemical modification of hyaluronic acid for intraoral application. Pharm. Sci., 103(8), 2414-2423.
  9. Laffleur, F. (2014). Mucoadhesive polymers for buccal drug delivery. Drug Dev Ind Pharm., 40(5), 591-598.
  10. Millotti, G.; Laffleur, F.; Perera, G.; Vigl, C.; Pickl, K.; Sinner, F.; Bernkop-Schnürch, A. (2014). In vivo evaluation of thiolated chitosan tablets for oral insulin delivery. Pharm. Sci., 103, 3165-3170.
  11. Millotti, G.; Vetter, A.; Leithner, K.; Sarti, F.; Shahnaz-Bano, G.; Augustijns, P.; Bernkop-Schnürch, A. (2014). Development of thiolated poly(acrylic acid) microparticles for the nasal administration of exenatide. Drug Dev. Ind. Pharm., 40, 1677-1682.
  12. Müller, C.; Perera, G.; König, V.; Bernkop-Schnürch, A. (2014). Development and in vivo evaluation of papain-functionalized nanoparticles. J. Pharm. Biopharm., 87, 125-131.
  13. Nowak, J.; Laffleur, F.; Bernkop-Schnürch, A. (2014). Preactivated hyaluronic acid: A potential mucoadhesive polymer for vaginal delivery. J. Pharm., 478, 383-389.
  14. Pereira de Sousa, I.; Bernkop-Schnürch, A. (2014). Pre-systemic metabolism of orally administered drugs and strategies to overcome it. Control. Rel., 192, 301-309.
  15. Samaridou, E.; Karidi, K.; Pereira de Sousa, I.; Cattoz, B.; Griffiths, P.; Kammona, O.; Bernkop-Schnürch, A.; Kiparissides. C. (2014). Enzyme-Functionalized PLGA Nanoparticles with Enhanced Mucus Permeation Rate. Nano LIFE, 4, 1441013
  16. Waldner, C.; Friedl, H.E.; Dünnhaupt, S.; Köllner, S.; Leonaviciute, G.; Bernkop-Schnürch, A. (2014). Development of a dosage form for accelerated release. J. Pharm., 471, 189-196.
  1. Barthelmes, J.; Dünnhaupt, S.; Unterhofer, S.; Perera, G.; Schlocker, W.; Bernkop-Schnürch, A. (2013). Thiolated particles as effective intravesical drug delivery systems for treatment of bladder-related diseases. Nanomedicine, 8(1), 65-75.
  2. Bernkop-Schnürch, A. (2013). Mucoadhesive polymers: Basics, Strategies and Future Trends. Buchbeitrag: Polymeric Biomaterials. 3rd edition (Ed. Severian Dumitriu) Marcel Dekker, New York 193-220.
  3. Bernkop-Schnürch, A. (2013). Reprint of: Nanocarrier systems for oral drug delivery: do we really need them? Eur. J. Pharm. Sci., 50(1), 2-7.
  4. Bernkop-Schnürch, A. (2013). Nanocarrier systems for oral drug delivery: Do we really need them? Eur. J. Pharm. Sci., 49(2), 272-277.
  5. Friedl, H.; Dünnhaupt, S.; Hintzen, F.; Waldner, C.; Parikh, S.; Pearson, J.P.; Wilcox, M.D.; Bernkop-Schnürch, A. (2013). Development and evaluation of a novel mucus diffusion test system approved by self-nanoemulsifying drug delivery systems. J. Pharm. Sci., 102(12), 4406-4413.
  6. Friedl, H.E.; Dünnhaupt, S.; Waldner, C.; Bernkop-Schnürch, A. (2013). Preactivated thiomers for vaginal drug delivery vehicles. Biomaterials, 34(32), 7811-7818.
  7. Gradauer, K.; Barthelmes, J.; Vonach, C.; Almer, G.; Mangge, H.; Teubl, B.; Roblegg, E.; Dünnhaupt, S.; Fröhlich, E.; Bernkop-Schnürch, A.; Prassl, R. (2013). Liposomes coated with thiolated chitosan enhance oral peptide delivery to rats. J. Control. Rel., 172(3), 872-878.
  8. Gradauer, K.; Dünnhaupt, S.; Vonach, C.; Szöllösi, H.; Pali-Schöll, I.; Mangge, H.; Jensen-Jarolim, E.; Bernkop-Schnürch, A.; Prassl, R. (2013). Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties. J. Control. Rel., 165, 207-215.
  9. Hauptstein, S.; Müller, C.; Dünnhaupt, S.; Laffleur, F.; Bernkop-Schnürch, A. (2013). Preactivated thiomers: Evaluation of gastroretentive minitablets. Int. J. Pharm., 456(2), 473-479.
  10. Hintzen, F.; Hauptstein, S.; Perera, G.; Bernkop-Schnürch, A. (2013). Synthesis and in vitro characterization of entirely S-protected thiolated pectin for drug delivery. Eur. J. Pharm. Biopharm., 85(3), 1266-1273.
  11. Hintzen, F.; Laffleur, F.; Sarti, F.; Müller, C.; Bernkop-Schnürch, A. (2013). In vitro and ex vivo evaluation of an intestinal permeation enhancing self-microemulsifying drug delivery system (SMEDDS). J. Drug Del.Sci. Tech., 23(3), 261-267.
  12. Laffleur, F.; Bernkop-Schnürch, A. (2013). Strategies for improving mucosal drug delivery. Nanomedicine, 8(12), 2061-2075.
  13. Laffleur, F.; Hintzen, F.; Rahmat, D.; Shahnaz, G.; Millotti, G.; Bernkop-Schnürch, A. (2013). Enzymatic degradation of thiolated chitosan. Drug Dev. Ind. Pharm., 39(10), 1531-1539.
  14. Laffleur, F.; Shahnaz, G.; Islambulchilar, Z.; Bernkop-Schnürch, A. (2013). Design and in vitro evaluation of a novel polymeric excipient for buccal applications. Future Med. Chem., 5(5), 511-522.
  15. Müller, C.; Leithner, K.; Hauptstein, S.; Hintzen, F.; Salvenmoser, W.; Bernkop-Schnürch, A. (2013). Preparation and characterization of mucus-penetrating papain/polyacrilic acid nanoparticles for oral drug delivery applications. Nanopart. Res., 15, 1353-1365.
  16. Müller, C.; Ma, B.N.; Gust, R.; Bernkop-Schnürch, A. (2013). Thiopyrazole preactivated chitosan: Combining mucoadhesion and drug delivery. Acta Biomater., 9(5), 6585-6593.
  17. Rahmat, D.; Müller, C.; Barthelmes, J.; Shahnaz, G.; Martien, R.; Bernkop-Schnürch, A. (2013). Thiolated hydroxyethyl cellulose: Design and in vitro evaluation of mucoadhesive and permeation enhancing nanoparticles. Eur. J. Pharm. Biopharm., 83, 149-155.
  18. Rahmat, D.; Müller, C.; Shahnaz, G.; Laffleur, F.; Leithner, K.; Khan, M.I.; Martien, R.; Bernkop-Schnürch, A. (2013). HEC-cysteamine particles: influence of particle size, zeta potential, morphology and sulfhydryl groups on permeation enhancing properties. Drug Dev. Ind. Pharm., 39, (9), 1338-1345.
  19. Sakloetsakun, D.; Dünnhaupt, S.; Barthelmes, J.; Perera, G.; Bernkop-Schnürch, A. (2013). Combining two technologies: Multifunctional polymers and self-nanoemulsifying drug delivery system (SNEDDS) for oral insulin administration. Int. J. Biol. Macromol., 61, 363-372.
  20. Sarti, F.; Müller, C.; Iqbal, J.; Perera, G.; Laffleur, F.; Bernkop-Schnürch, A. (2013). Development and in vivo evaluation of an oral vitamin B12 delivery system. Eur. J. Pharm. Biopharm., 84, 132-137.
  21. Shahnaz, G.; Kremser, C.; Reinisch, A.; Vetter. A.; Laffleur, F.; Rahmat, D.; Iqbal, J.; Dünnhaupt, S.; Salvenmoser, W.; Tessadri, R.; Griesser, U.; Bernkop-Schnürch, A. (2013). Efficient MRI labeling of endothelial progenitor cells: Design of thiolated surface stabilized superparamagnetic iron oxide nanoparticles. Eur. J. Pharm. Biopharm., 85(3), 346-355.
  1. Bernkop-Schnürch, A.; Dünnhaupt, S. (2012). Chitosan based drug delivery systems. Eur. J. Pharm. Biopharm., 81, 463-469.
  2. Boonpisuttinant, K.; Manosroi, A.; Rahmat, D.; Manosroi, J. (2012). In Vitro Intestinal Membrane Permeation Enhancement of Thai Anti-Cancer Recipe Aqueous Extracts Loaded inThiolated-Chitosan Nanoparticles. Adv. Sci. Lett. 16, 183-192.
  3. Dünnhaupt, S.; Barthelmes, J.; Iqbal, J.; Perera, G.; Thurner, C.C.; Friedl, H.; Bernkop-Schnürch, A. (2012). In vivo evaluation of an oral drug delivery system for peptides based on S-protected thiolated chitosan. J. Control. Rel., 160, 477-485.
  4. Dünnhaupt, S.; Barthelmes, J.; Rahmat, D.; Leithner, K.; Thurner, C.C.; Friedl, H.; Bernkop-Schnürch, A. (2012). S-protected thiolated chitosan for oral delivery of hydrophilic macromolecules: Evaluation of permeation enhancing and efflux pump inhibitory properties. Mol. Pharm., 9, 1331-1341.
  5. Dünnhaupt, S.; Barthelmes, J.; Thurner, C.C.; Waldner, C.; Sakloetsakun, D.; Bernkop-Schnürch, A. (2012). S-protected thiolated chitosan: synthesis and in vitro characterization. Carbohydr. Polym., 90, 765-772.
  6. Erb, R.; Leithner, K.; Bernkop-Schnürch, A.; Oberacher, H. (2012). Phosphorothioate Oligonucleotide Quantification by μ-Liquid Chromatography-Mass Spectrometry. AAPS Journal, 14, 728-737.
  7. Gradauer, K.; Vonach, C.; Leitinger, G.; Kolb, D.; Fröhlich, E.; Roblegg, E.; Bernkop-Schnürch, A.; Prassl, R. (2012). Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties. Int. J. Nanomedicine, 7, 2523-2534.
  8. Hauptstein, S.; Bernkop-Schnürch, A. (2012). Thiomers and thiomer-based nanoparticles in protein and DNA drug delivery. Expert Opinion Drug Deliv., 9, 1069-1081.
  9. Hintzen, F.; Laffleur, F.; Sakloetsakun, D.; Leithner, K.; Bernkop-Schnürch, A. (2012). In situ gelling properties of anionic thiomers. Drug Dev. Ind. Pharm., 38, 1479-1485.
  10. Hintzen, F.; Laffleur, F.; Sarti, F.; Shahnaz, G.; Bernkop-Schnürch, A. (2012). Thiomers: Influence of molar mass on in situ gelling properties. Int. J. Pharm., 436, 120-126.
  11. Iqbal, J.; Shahnaz, G.; Dünnhaupt, S.; Müller, C.; Hintzen, F.; Bernkop-Schnürch, A. (2012). Preactivated thiomers as mucoadhesive polymers for drug delivery. Biomaterials, 33, 1528-1535.
  12. Iqbal, J.; Shahnaz, G.; Perera, G.; Hintzen, F.; Sarti, F.; Bernkop-Schnürch, A. (2012). Thiolated chitosan: Development and in vivo evaluation of an oral delivery system for leuprolide. Eur. J. Pharm. Biopharm., 80, 95-102.
  13. Laffleur, F.; Bernkop-Schnürch, A. (2012). Thiomers: promising platform for macromolecular drug delivery. Future Med. Chem., 4, 2205-2216.
  14. Müller, C.; Rahmat, D.; Sarti, F.; Leithner, K.; Bernkop-Schnürch, A. (2012). Immobilization of 2-mercaptoethylamine on oxidized chitosan: a substantially mucoadhesive and permeation enhancing polymer. J. Mater. Chem., 22, 3899-3908. (2012)
  15. Müller, C.; Verroken, A.; Iqbal, J.; Bernkop-Schnürch, A. (2012). Thiolated Chitosans: in vitro comparison of mucoadhesive properties. J. Appl. Polym. Sci., 124, 5046-5055.(2012)
  16. Perera, G.; Bernkop-Schnürch, A. (2012). Pharmaceutical Non-Viral Formulations for Gene Vaccines. Buchbeitrag: Gene Vaccines Ed. Thalhammer Josef. 109-125.
  17. Rahmat, D.; Khan, M.I.; Shahnaz, G.; Sakloetsakun, D.; Perera, G.; Bernkop-Schnürch, A. (2012). Synergistic effects of conjugating cell penetrating peptides and thiomers.
  18. On non-viral transfection efficiency. Biomaterials, 33, 2321-2326.
  19. Rahmat, D.; Sakloetsakun, D.; Shahnaz, G.; Sarti, F.; Laffleur, F.; Bernkop-Schnürch, A. (2012). HEC-cysteamine conjugates: Influence of degree of thiolation on efflux pump inhibitory and permeation enhancing properties. Int. J. Pharm., 422, 40-46.
  20. Sakloetsakun, D.; Dünnhaupt, S.; Barthelmes, J.; Pfaller, W.; Bernkop-Schnürch, A. (2012). In situ crosslinkable thiolated chitosan as scaffold material for tissue engineering. Adv. Mat. Res., 506, 335-338.
  21. Sarti, F.; Iqbal, J.; Müller, C.; Shahnaz, G.; Rahmat, D.; Bernkop-Schnürch, A. (2012). Poly(acrylic acid)-cysteine for oral vitamin B12 delivery. Anal. Biochem., 420, 13-19.
  22. Shahnaz, G.; Iqbal, J.; Rahmat, D.; Perera, G.; Laffleur, F.; Rossi, D.; Bernkop-Schnürch, A. (2012). Development and in vivo characterization of a novel peptide drug delivery system providing extended plasma half life. J. Control. Rel., 157, 375-382.
  23. Shahnaz, G.; Vetter, A.; Barthelmes, J.; Rahmat, D.; Laffleur, F.; Iqbal, J.; Perera, G.; Schlocker, W.; Dünnhaupt, S.; Augustijns, P.; Bernkop-Schnürch, A. (2012). Thiolated chitosan nanoparticles for the nasal administration of leuprolide: Bioavailability and pharmacokinetic characterization. Int. J. Pharm., 428, 164-170.
  24. Solhi, L.; Schönbichler, S.A.; Dünnhaupt, S.; Barthelmes, J.; Friedl, H.; Huck, C.W.; Bernkop-Schnürch, A. (2012). Synthesis and In Vitro Characterization of a Preactivated Thiomer via Polymerization Reaction. Biomacromolecules, 13, 3054-3063.
  25. Vetter, A.; Augustijns, P.; Bernkop-Schnürch, A. (2012). Solubilizing agents in nasal formulations and their effect on ciliary beat frequency. Toxicol. in vitro, 26, 150-156.
  26. Wang, X.; Iqbal, J.; Rahmat, D.; Bernkop-Schnürch, A. (2012). Preactivated thiomers: Permeation enhancing properties. Int. J. Pharm., 438, 217-224.
  1. Baloglu, E.; Ay Senyıgıt, Z.; Karavana, S.Y.; Vetter, A.; Metın, D.Y.; Hilmioglu Polat, S.; Guneri, T.; Bernkop-Schnürch, A. (2011). In vitro evaluation of mucoadhesive vaginal tablets of antifungal drugs prepared with thiolated polymer and development of a new dissolution technique for vaginal formulations Chem.Pharm.Bull., 59, 952-958.
  2. Barthelmes, J.; Dünnhaupt, S.; Hombach, J.; Bernkop-Schnürch, A. (2011). Thiomer nanoparticles: Stabilization via covalent cross-linking. Drug Deliv., 18, 613-619.
  3. Barthelmes, J.; Perera, G.; Hombach, J.; Dünnhaupt, S.; Bernkop-Schnürch, A. (2011). Development of a mucoadhesive nanoparticulate drug delivery system for a targeted drug release in the bladder. Int. J. Pharm., 416, 339-345.
  4. Dudas, J.; Idler, C.; Sprinzl,G.; Bernkop-Schnuerch, A.; Riechelmann, H. (2011). Identification of HN-1-Peptide Target in Head and Neck Squamous Cell Carcinoma Cells. ISRN Oncology Article ID 140316, 10 pages
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  6. Dünnhaupt, S.; Barthelmes, J.; Hombach, J.; Sakloetsakun, D.; Arkhipova, V.; Bernkop-Schnürch, A. (2011). Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa. Int. J. Pharm., 408, 191-199.
  7. Hoyer, H.; Hombach, J.; Perera, G.; Thaurer, M.; Bernkop-Schnürch, A. (2011). Synthesis and in vitro characterization of a novel PAA-ATP conjugate. Drug Dev. Ind. Pharm., 37, 300-309.
  8. Iqbal, J.; Sakloetsakun, D.; Bernkop-Schnürch, A. (2011). Thiomers: Inhibition of cytochrome P450 activity. Eur. J. Pharm. Biopharm., 78, 361-365.
  9. Iqbal, J.; Sarti, F.; Perera, G.; Bernkop-Schnürch, A. (2011). Development and in vivo evaluation of an oral drug delivery system for paclitaxel. Biomaterials, 32, 170-175.
  10. Iqbal, J.; Vigl, C.; Moser, G.; Gasteiger, M.; Perera, G.; Bernkop-Schnürch, A. (2011). Development and in vivo evaluation of a new oral nanoparticulate dosage form for leuprolide based on polyacrylic acid. Drug Deliv., 18, 432-440.
  11. Leithner, K.; Grabovac, V.; Albrecht, K.; Hombach, J.; Klima, G.; Bernkop-Schnürch, A. (2011). Permeation studies on freshly excised rat gastric mucosa: influence of pH. Drug Dev. Ind. Pharm., 37, 518-525.
  12. Llabot, J.M.; Salman, H.; Millotti, G.; Bernkop-Schnürch, A.; Allemandi, D.; Manuel Irache, J. (2011). Bioadhesive properties of poly(anhydride) nanoparticles coated with different molecular weights chitosan. J. Microencap., 28, 455-463.
  13. Martien, R.; Hoyer, H.; Perera, G.; Bernkop-Schnürch, A. (2011). An oral oligonucleotide delivery system based on a thiolated polymer: Development and in vitro evaluation. Eur. J. Pharm. Biopharm., 78, 355-360.
  14. Millotti, G.; Perera, G.; Vigl, C.; Pickl, K.; Sinner, F.M.; Bernkop-Schnürch, A. (2011). The use of chitosan-6-mercaptonicotinic acid nanoparticles for oral peptide drug delivery. Drug Deliv., 18, 190-197.
  15. Palmberger, T.; Augustijns, P.; Vetter, A.; Bernkop-Schnürch, A. (2011). Safety assessment of thiolated polymers: effect on ciliary beat frequency in human nasal epithelial cells. Drug Dev. Ind. Pharm., 37, 1455-1462.
  16. Perera, G.; Barthelmes, J.; Vetter, A.; Krieg, C.; Uhlschmied, C.; Bonn, G.K.; Bernkop-Schnürch, A. (2011). Thiolated polycarbophil/glutathione: Defining its potential as a permeation enhancer for oral drug administration in comparison to sodium caprate. Drug Deliv., 18, 415-423.
  17. Rahmat, D.; Sakloetsakun, D.; Shahnaz, G.; Perera, G.; Kaindl, R.; Bernkop-Schnürch, A. (2011). Design and synthesis of a novel cationic thiolated polymer. Int. J. Pharm., 411, 10-17.
  18. Sakloetsakun, D.; Iqbal, J.; Millotti, G.; Vetter, A.; Bernkop-Schnürch, A. (2011). Thiolated chitosans: influence of various sulfhydryl ligands on permeation-enhancing and P-gp inhibitory properties. Drug Dev. Ind. Pharm., 37, 648-655.
  19. Sarti, F.; Barthelmes, J.; Iqbal, J.; Hintzen, F.; Bernkop-Schnürch, A. (2011). Intestinal enzymatic metabolism of drugs. J. Pharm. Pharmacol., 63, 392-399.
  20. Sarti, F.; Bernkop-Schnürch, A. (2011). Chitosan and Thiolated Chitosan. Adv. Polym. Sci., 243, 93-110.
  21. Sarti, F.; Perera, G.; Hintzen, F.; Kottib,K.; Karageorgioub, V.; Kammonab, O.; Kiparissides, C.; Bernkop-Schnürch, A. (2011). In vivo evidence of oral vaccination with PLGA nanoparticles containing the immunostimulant monophosphoryl lipid A. Biomaterials, 32, 4052-4057.
  22. Senyigit, Z.A.; Vetter, A.; Guneri, T.; Bernkop-Schnürch, A. (2011). A comprehensive in vitro and in vivo evaluation of thiolated matrix tablets as a gastroretentive delivery system. Drug Deliv., 18, 405-414.
  23. Shahnaz, G.; Hartl, M.; Barthelmes, J.; Leithner, K.; Sarti, F.; Hintzen, F.; Rahmat, D.; Salvenmoser, W.; Bernkop-Schnürch, A. (2011). Uptake of phenothiazines by the harvested chylomicrons ex vivo model: Influence of self-nanoemulsifying formulation design. Eur. J. Pharm. Biopharm., 79, 171-180.
  24. Vetter, A.; Reinisch, A.; Strunk, D.; Kremser, C.; Hahn, H.W.; Huck, C.W.; Ostermann, T.; Leithner, K.; Bernkop-Schnürch, A. (2011). Thiolated polyacrylic acid-modified iron oxide nanoparticles for in vitro labeling and MRI of stem cells. J. Drug Targ., 19, 562-572.
  1. Albrecht, K.; Greindl, M.; Deutel, B.; Kremser, C.; Wolf, C.; Talasz, H.; Stollenwerk, M.; Debbage, P.; Bernkop-Schnürch, A.(2010).In vivo investigation of thiomer-polyvinylpyrrolidon nanoparticles using magnetic resonance imaging.J. Pharm. Sci., 99, 2008-2017.
  2. Hombach, J.; Bernkop-Schnürch, A.(2010).Mucoadhesive drug delivery systems.Handbook of Experimental Pharmacology Ed Monika Schäfer-Korting Springer Heidelberg. 251-266.
  3. Hoyer, H.; Perera, G.; Bernkop-Schnürch, A.(2010).Noninvasive delivery systems for peptides and proteins in osteoporosis therapy: a retroperspective.Drug Dev. Ind. Pharm., 36, 31-44.
  4. Hoyer, H.; Schlocker, W.; Greindl, M.; Ostermann, T.; Bernkop-Schnürch, A.(2010).Preparation and evaluation of thiomer nanoparticles via high pressure homogenization.J. Microencap., 27(6), 487-495.
  5. Iqbal, J.; Hombach, J.; Matuszczak, B.; Bernkop-Schnürch, A.(2010).Design and in vitro evaluation of a novel polymeric P-glycoprotein (P-gp) inhibitorJ. Control. Rel., 147, 62-69.
  6. Millotti, G.; Hoyer, H.; Engbersen, J.F.J.; Bernkop-Schnürch, A.(2010).6-mercaptonicotinamide- functionalized chitosan: A potential excipient for mucoadhesive drug delivery systems.J. Drug Del. Sci.Tech., 20, 181-186.
  7. Perera, G.; Barthelmes, J.; Bernkop-Schnürch, A.(2010).Novel pectin-4-aminothiophenole conjugate microparticles for colon-specific drug delivery.J. Control. Rel., 145, 240-246.
  8. Perera, G.; Hombach, J.; Bernkop-Schnürch, A.(2010).Hydrophobic thiolation of pectin with 4-aminothiophenol: Synthesis and in vitro characterization.AAPS PharmSciTech., 11, 174-180.
  9. Sakloetsakun, D.; Bernkop-Schnürch, A.(2010).Thiolated Chitosans.J. Drug Del. Sci.Tech., 20, 63-69.
  10. Sakloetsakun, D.; Perera, G.; Hombach, J.; Millotti, G.; Bernkop-Schnürch, A. (2010). The impact of vehicles on the mucoadhesive properties of orally administered nanoparticles: a cas. AAPS PharmSciTech., 11, 1185-1192.
  11. Sarti, F.; Staaf, A.; Sakloetsakun, D.; Bernkop-Schnürch, A. (2010). Thiolated hydroxyethylcellulose:synthesis and in vitro evaluation. Eur. J. Pharm. Biopharm., 76, 421-427.
  12. Senyigit, Z.A.; Vetter, A.; Guneri, T.; Bernkop-Schnürch, A. (2010). Gastroretentive particles formulated with thiomers: development and in vitro evaluation. J. Drug Targ., 18, 362-372.
  13. Shahnaz, G.; Perera, G.; Sakloetsakun, D.; Rahmat, D.; Bernkop-Schnürch, A. (2010). Synthesis, Characterization, Mucoadhesion and Biocompatibility of Thiolated Carboxymethyldextran-Cysteine Conjugate. J. Control. Rel., 144, 32-38.
  14. Vetter, A.; Bernkop-Schnürch, A. (2010). Nasal delivery of antisense oligonucleotides: in vitro evaluation of a thiomer/glutathione microparticulate delivery system. J. Drug Targ., 18, 303-312.
  15. Vetter, A.; Martien, R.; Bernkop-Schnürch, A. (2010). Thiolated polycarbophil as an adjuvant for permeation enhancement in nasal delivery of antisense oligonucleotides. J. Pharm. Sci., 99, 1427-1439.
  16. Vetter, A.; Perera, G.; Leithner, K.; Klima, G.; Bernkop-Schnürch, A. (2010). Development and in vivo bioavailability study of an oral fondaparinux delivery system. Eur. J. Pharm. Sci., 41, 489-497.
  1. Baloglu, E.; Senyigit, Z.A.; Karavana, S.Y.; Bernkop-Schnürch, A. (2009). Strategies to prolong the intravaginal residence time of drug delivery systems. J.Pharm.Pharmaceut.Sci., 12, 312-336.
  2. Bernkop-Schnürch, A. (2009). Low molecular mass permeation enhancers in oral delivery of molecular drugs. Oral Delivery of Macromolecular Drugs: Barriers, Strategies and Future Trends. 85-101.
  3. Biasutto, L.; Marotta, E.; Mattarei, A.; Beltramello, S.; Caliceti, P.; Salmaso, S. Bernkop-Schnürch, A.; Garbisa, S; Zoratti, M.; Paradisi, C. (2009). Absorption and metabolism of resveratrol carboxyesters and methanesulfonate by explanted rat intestinal segments. Cellular Physiology and Biochemistry, 24, 557-566.
  4. Figueiras, A.; Hombach, J.; Veiga, F.; Bernkop-Schnürch A. (2009). In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing systems for omeprazole delivery. Eur. J. Pharm. Biopharm., 71, 339-345.
  5. Greindl, M.; Föger, F.; Hombach, J.; Bernkop-Schnürch, A. (2009). In vivo evaluation of thiolated poly(acrylic acid) as a drug absorption modulator for MRP2 efflux pump substrates. Eur. J. Pharm. Biopharm., 72, 561-566.
  6. Hombach, J.; Bernkop-Schnürch, A. (2009). Mucoadhesive drug delivery systems. Handbook of Experimental Pharmacology Ed Monika Schäfer-Korting Springer Heidelberg.
  7. Hombach, J.; Bernkop-Schnürch, A. (2009). Chitosan solutions and particles: Evaluation of their permeation enhancing potential on MDCK cells used as blood brain barrier model. Int. J. Pharm., 376, 104-109.
  8. Hombach, J.; Palmberger, T.; Bernkop-Schnürch, A. (2009). Development and in vitro evaluation of a mucoadhesive vaginal delivery system for nystatin. J. Pharm. Sci., 98, 555-564.
  9. Hoyer, H.; Greindl, M.; Bernkop-Schnürch, A. (2009). Design and in vivo evaluation of a patch system based on thiolated polymers. J. Pharm. Sci., 98, 620-627.
  10. Millotti, G.; Samberger, C.; Fröhlich, E.; Bernkop-Schnürch, A. (2009). Chitosan-graft-6-mercaptonicotinic acid: synthesis, characterization, and biocompatibility. Biomacromolecules, 10, 3023-3027.
  11. Perera, G.; Greindl, M.; Palmberger, T.; Bernkop-Schnürch, A. (2009). Insulin-loaded poly(acrylic acid)-cysteine nanoparticles: stability studies towards digestive enzymes of the intestine. Drug Deliv., 16, 254-260.
  12. Sakloetsakun D.; Hombach J.; Bernkop-Schnürch, A. (2009). In situ gelling properties of chitosan-thioglycolic acid conjugate in the presence of oxidizing agents. Biomaterials, 31, 6151-6157.
  13. Thaurer, M.H.; Deutel, B.; Schlocker, W.; Bernkop-Schnürch, A. (2009). Development of nanoparticulate drug delivery systems based on thiolated poly(acrylic acid). J. Microencap., 26, 187-194.
  14. Vigl, C.; Leithner, K.; Albrecht, K.; Bernkop-Schnürch, A. (2009). The efflux pump inhibitory properties of (thiolated) polyallylamines J. Drug Del. Sci.Tech., 19, 405-411.
  15. Werle, M.; Takeuchi, H.; Bernkop-Schnürch, A. (2009). Modified Chitosans for oral drug delivery. J. Pharm. Sci., 98, 1643-1656.
  1. Bernkop-Schnürch, A. (2008). Thiolated chitosans in non-invasive drug delivery. Natural-based polymers for biomedical applications. 624-643.
  2. Deutel, B.; Greindl, M.; Thaurer, M.; Bernkop-Schnürch, A. (2008). Novel insulin thiomer nanoparticles: in vivo evaluation of an oral drug delivery system. Biomacromolecules, 9, 278-285.
  3. Föger, F.; Kopf, A.; Loretz, B.; Albrecht, K.; Bernkop-Schnürch, A. (2008). Correlation of in vitro and in vivo models for the oral absorption of peptide drugs. Amino Acids, 35, 233-241.
  4. Föger, F.; Malaivijitnond,. S.; Wannaprasert, T.; Huck, C.; Bernkop-Schnürch, A.; Werle, M. (2008). Effect of a thiolated polymer on oral paclitaxel absorption and tumor growth in rats. J. Drug Targ., 16, 149-155.
  5. Grabovac, V.; Föger, F.; Bernkop-Schnürch, A. (2008). Design and in vivo evaluation of a patch delivery system for insulin based on thiolated polymers. Int. J. Pharm., 348, 169-174.
  6. Hombach, J.; Hoyer, H.; Bernkop-Schnürch, A. (2008). Thiolated chitosans: Development and in vitro evaluation of an oral tobramycin sulphate delivery system. Eur. J. Pharm. Sci., 33, 1-8.
  7. Hoyer, H.; Schlocker, W.; Kafedjiiski, K.; Bernkop-Schnürch, A. (2008). Preparation and evaluation of microparticles from thiolated polymers via air jet milling. Eur. J. Pharm. Biopharm., 69, 476-485.
  8. Kremser, C.; Albrecht, K.; Greindl, M.; Wolf, C.; Debbage, P.; Bernkop-Schnürch, A. (2008). In vivo determination of time and location at which mucoadhesive drug delivery systems disintegrate in the gastrointestinal tract. Magn. Reson. Imaging, 26, 638-643.
  9. Martien, R.; Loretz, B.; Sandbichler, A.M.; Bernkop-Schnürch, A. (2008). Thiolated chitosan nanoparticles: transfection study in the Caco-2 differentiated cell culture. Nanotechnology, 19, 045101 (9pp).
  10. Palmberger, T.; Hombach, J.; Bernkop-Schnürch, A. (2008). Thiolated chitosan: Development and in vitro evaluation of an oral delivery system for acyclovir. Int. J. Pharm., 348, 54-60.
  11. Petter, Ch.; Heigl, N.; Bachmann, St.; Huck-Pezzei, V.; Najam-ol-Haq, M.; Bakry, R.; Bernkop-Schnürch, A.; Bonn, G.; Huck, Ch. (2008). Near infrared spectroscopy compared to liquid chromatography coupled to mass spectrometry and capillary electrophoresis as a detection tool for peptide reaction monitoring. Amino Acids, 34, 605-616.
  12. Schmitz, T.; Grabovac, V.; Palmberger, T.F.; Hoffer, M.H.; Bernkop-Schnürch, A. (2008). Synthesis and characterization of a chitosan-N-acetyl cystein conjugate. Int. J. Pharm., 347, 79-85.
  13. Schmitz, T.; Hombach, J.; Bernkop-Schnürch, A. (2008). Chitosan-N-acetyl cysteine conjugates: In vitro evaluation of permeation enhancing and P-glycoprotein inhibiting properties. Drug Deliv., 15, 245-252.
  14. Tsiklauri, L.; Hoyer, H.; Chkhikvadze, G.; Vachnadze, V.; Tsagareishvili, G.; Bakuridze, A.; Bernkop-Schnurch, A. (2008). Role of P-glycoproteins (P-gp) in the transepithelial transport of indoline alkaloids from Vinca herbaceae. Khim.-Farm. Zhurnal, 42, 29-32.
  15. Werle, M.; Bernkop-Schnürch, A. (2008). Thiolated chitosans: useful excipients for oral drug delivery. J. Pharm. Pharmacol., 60, 273-281.
  16. Werle, M.; Kolmar, H.; Albrecht, R.; Bernkop-Schnürch, A. (2008). Characterisation of the barrier caused by luminally secreted gastro-intestinal proteolytic enzymes for two novel cystine-knot microproteins. Amino Acids, 35, 195-200.
  1. Albrecht, K. and Bernkop-Schnürch, A. (2007). Thiomers: forms, functions and applications to nanomedicine. Nanomedicine, 2, 41-50.
  2. Bernkop-Schnürch, A. and Schmitz, Th. (2007). Presystemic metabolism of orally administered peptide drugs and strategies to overcome it. Curr. Drug Metab., 8, 509-517.
  3. Föger, F., Kafedjiiski, K., Hoyer, H., Loretz, B. and Bernkop-Schnürch, A. (2007). Enhanced transport of P-glycoprotein substrate saquinavir in presence of thiolated chitosan. J. Drug Targ., 15, 132-139.
  4. Grabovac, V. and Bernkop-Schnürch, A. (2007). Development and in vitro evaluation of surface modified poly(lactide-co-glycolide) nanoparticles with chitosan-4-thiobutylamidine. Drug Dev. Ind. Pharm., 33, 767-774.
  5. Grabovac, V., Schmitz, Th., Föger, F. and Bernkop-Schnürch, A. (2007). Papain: An effective permeation enhancer for orally administered low molecular weight heparin. Pharm. Res., 24, 1001-1006.
  6. Greimel, A., Del Curto, M. D., D’Antonio, M. and Bernkop-Schnürch, A. (2007). Transport characteristics of a beta sheet breaker peptide across excised bovine nasal mucosa. Drug Dev. Ind. Pharm., 33, 71-77.
  7. Greimel, A., Werle, M. and Bernkop-Schnürch, A. (2007). Oral peptide delivery: in vitro evaluation of thiolated alginate / poly(acrylic acid) microparticles. J. Pharm. Pharmacol., 59, 1191-1198.
  8. Hoyer, H., Föger, F., Kafedjiiski, K., Loretz, B., and Bernkop-Schnürch, A. (2007). Design and evaluation of a new gastrointestinal mucoadhesive patch system containing chitosan-glutathione. Drug Dev. Ind. Pharm., 33, 1289-1296.
  9. Kafedjiiski, K., Föger, F., Hoyer, H., Werle, M. and Bernkop-Schnürch, A. (2007). Evaluation of in vitro enzymatic degradation of various thiomers and cross-linked thiomers. Drug Dev. Ind. Pharm., 33, 199-208.
  10. Kafedjiiski, K., Jetti, R., Föger, F., Hoyer, H., Werle, M., Hoffer, M., and Bernkop-Schnürch, A. (2007). Synthesis and in vitro evaluation of thiolated hyaluronic acid for mucoadhesive drug delivery. Int. J. Pharm., 343, 48-58.
  11. Loretz, B. and Bernkop-Schnürch, A. (2007). In vitro cytotoxity testing of non-thiolated and thiolated chitosan nanoparticles for oral gene delivery. Nanotoxicology, 1, 139-148.
  12. Loretz, B., Thaler, M. and Bernkop-Schnürch, A. (2007). Role of sulfhydryl groups in transfection? A case study with chitosan-NAC nanoparticles. Bioconjugate Chemistry, 18, 1028-1035.
  13. Martien, R., Loretz, B., Thaler, M., Majzoob, S. and Bernkop-Schnürch, A. (2007). Chitosan-thioglycolic acid conjugate: An alternative carrier for oral non-viral gene delivery? J. Biomed. Mat. Res. A., 82, 1-9.
  14. Palmberger, T. F., Albrecht, K, Loretz, B., and Bernkop-Schnürch, A. (2007). Thiolated polymers: Evaluation of the influence of the amount of covalently attached l-cysteine to poly(acrylic acid). Eur. J. Pharm. Biopharm., 66, 405-412.
  15. Schmitz, T., Bravo-Osuna, I., Vauthier, C., Ponchel, G., Loretz, B. and Bernkop-Schnürch, A. (2007). Development and in vitro evaluation of a thiomer-based nanoparticulate gene delivery system. Biomaterials, 28, 524-531. 2006
  16. Werle, M, Hsu, Y. T., Chang, F. C., Lee, Ch. H. (2007). Analytical Methods for the Characterisation of Multifunctional Polymers for Oral Drug Delivery. Current Pharmaceutical Analysis, 3, 111-116.
  17. Werle, M. and Bernkop-Schnürch, A. (2007). Inhibition of enzymes and secretory transport. Enhancement in drug delivery Elka Touitou and Brian W. Barry CRC Press 85-109.
  18. Werle, M., Kafedjiiski, K., Kolmar H. and Bernkop-Schnürch, A. (2007). Evaluation and improvement of the properties of the novel cystine-knot microprotein McoEeTI for oral administration. Int. J. Pharm., 332, 72-79.
  19. Werle, M., Kolmar, H., and Bernkop-Schnürch, A. (2007). Relation between scaffold size and membrane bound enzyme caused degradation of two novel cystine knot microproteins. Letters in Drug Design & Discovery, 4, 33-36.
  20. Werle, M., Loretz, B., Entstrasser, D. and Föger, F. (2007). Design and evaluation of a chitosan-aprotinin conjugate for the peroral delivery of therapeutic peptides and proteins susceptible to enzymatic degradation. J. Drug Targ., 15, 327-333.
  1. Albrecht, K., Greindl, M.; Kremser, C.; Wolf, C.; Debbage, P. and Bernkop-Schnürch, A. (2006). Comparative in vivo mucoachesion studies of thiomer formulations using magnetic resonance imaging and fluorescence detection. J. Control. Rel., 115, 78-84.
  2. Albrecht, K., Zirm, E.J., Palmberger, T.F., Schlocker, W. and Bernkop-Schnürch, A. (2006). Preparation of thiomer microparticles and in vitro evaluation of parameters influencing their mucoadhesive properties. Drug Dev. Ind. Pharm., 32, 1149-1157.
  3. Bernkop-Schnürch, A. (2006). Oral delivery of therapeutic peptides: Barriers and strategies to overcome them. J. Drug Targ., 14, 107-108.
  4. Bernkop-Schnürch, A. and Grabovac V. (2006). Polymeric efflux pump inhibitors in oral drug delivery. Am. J. Drug. Deliv., 4, 263-272.
  5. Bernkop-Schnürch, A., Heinrich, A. and Greimel, A. (2006). Development of a novel method for the preparation of submicron particles based on thiolated chitosan. Eur. J. Pharm. Biopharm., 63, 166-172.
  6. Bernkop-Schnürch, A., Obermair, K., Greimel, A. and Palmberger Th. F. (2006). In vitro evaluation of the potential of thiomers for the nasal administration of Leu-enkephalin. Amino Acids, 30, 417-423.
  7. Bernkop-Schnürch, A., Weithaler, A., Albrecht, K. and Greimel, A.
  8. Thiomers: Preparation and in vitro evaluation of a mucoadhesive nanoparticulate drug delivery system (2006). Thiomers: Preparation and in vitro evaluation of a mucoadhesive nanoparticulate drug delivery system. Int. J. Pharm., 317, 76-81.
  9. Bravo-Osuna, I., Schmitz, Th., Bernkop-Schnürch, A., Vauthier, Ch. and Ponchel, G. (2006). Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles. Int. J. Pharm., 316, 170-175.
  10. Föger, F., Hoyer, H., Kafedjiiski, K., Thaurer, M. and Bernkop-Schnürch, A (2006). In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein. Biomaterials, 27, 5855-5860.
  11. Föger, F., Noonpakdee, W., Loretz, B., Joojuntr, S., Salvenmoser, W. and Bernkop-Schnürch, A. (2006). Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles. Int. J. Pharm., 319, 139-146.
  12. Föger, F., Schmitz, T. and Bernkop-Schnürch, A. (2006). In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan. Biomaterials, 27, 4250-4255.
  13. Grabovac, V. and Bernkop-Schnürch, A. (2006). Improvement of the intestinal membrane permeability of low molecular weight heparin by complexation with stem bromelain. Int. J. Pharm., 326, 153-159.
  14. Greimel, A., Del Curto, M. D., D’Antonio, M., Palmberger, Th., Sprinzl, G. M. and Bernkop-Schnürch, A. (2006). In vitro evaluation of thiomer microparticles for nasal drug delivery. J. Drug Del. Sci.Tech., 16, 103-108.
  15. Greindl, M. and Bernkop-Schnürch, A. (2006). Development of a novel method for the preparation of thiolated polyacrylic acid nanoparticles. Pharm. Res., 23, 2183-2189.
  16. Huck, Ch. W., Pezzei, V., Schmitz, Th., Bonn, G.K. and Bernkop-Schnürch, A. (2006). Oral peptide delivery: Are there remarkable effects on drugs through sulfhydryl conjugation? J. Drug Targ., 14, 117-125.
  17. Kafedjiiski, K., Hoffer, M., Werle, M.and Bernkop-Schnürch, A. (2006). Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate. Biomaterials, 27, 127-135.
  18. Krauland, A., Guggi, D., and Bernkop-Schnürch, A. (2006). Thiolated chitosan microparticles: A vehicle for nasal peptide drug delivery. Int. J. Pharm., 307, 270-277.
  19. Krauland, A., Leitner, V. M., Grabovac, V. and Bernkop-Schnürch, A. (2006). In vivo evaluation of a nasal insulin delivery system based on thiolated chitosan. J. Pharm. Sci., 95, 2463-2472.
  20. Langoth, N., Kahlbacher, H., Schöffmann, G., Schmerold, I., Schuh, M., Franz, S., Kurka, P. and Bernkop-Schnürch A. (2006). Thiolated chitosans: Design and in vivo evaluation of a mucoadhesive buccal peptide drug delivery system. Pharm. Res., 23, 573-579.
  21. Loretz, B. and Bernkop-Schnürch, A. (2006). In vitro evaluation of chitosan-EDTA conjugate polyplexes as nanoparticulate gene delivery system. AAPS Journal, 8, E756-E764.
  22. Loretz, B., Föger, F. A., Werle, M. and Bernkop-Schnürch, A. (2006). Oral gene delivery: Strategies to improve stability of pDNA towards intestinal digestion. J. Drug Targ., 14, 311-319.
  23. Majzoob, S., Atyabi, F., Dorkoosh, F., Kafedjiiski, K., Loretz, B., and Bernkop-Schnürch, A. (2006). Pectin-cysteine conjugate: synthesis and in-vitro evaluation of its potential for drug delivery. J. Pharm. Pharmacol., 58, 1601-1610.
  24. Martien, R., Loretz, B., and Bernkop-Schnürch, A. (2006). Oral gene delivery: Design of polymeric carrier systems shielding towards intestinal enzymatic attack. Biopolymers, 83, 327-336.
  25. Schlocker, W., Gschließer, S. and Bernkop-Schnürch, A. (2006). Evaluation of the potential of air jet milling for peptide-loaded microparticle preparation. Eur. J. Pharm. Biopharm., 62, 260-266.
  26. Schmitz, T., Huck, C.W. and Bernkop-Schnürch, A. (2006). Characterisation of the thiol-disulphide chemistry of desmopressin by LC, µ-LC, LC-ESI-MS and Maldi-Tof. Amino Acids, 30, 35-42.
  27. Werle, M. and Bernkop-Schnürch, A. (2006). Strategies to improve plasma half life time of peptide and protein drugs. Amino Acids, 30, 351-367.
  28. Werle, M., Samhaber A. and Bernkop-Schnürch, A. (2006). Degradation of teriparatide by gastro-intestinal proteolytic enzymes. J. Drug Targ., 14, 109-115.
  29. Werle, M., Schmitz, Th., Huang, H.-L., Wentzel, A., Kolmar, H. and Bernkop-Schnürch A. (2006). The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery. J. Drug Targ., 14, 137-146.
  1. Bernkop-Schnürch, A. (2005). Thiomers: A new generation of mucoadhesive polymers. Adv. Drug Del. Rev., 57, 1569-1582.
  2. Bernkop-Schnürch, A. (2005). Mucoadhesive polymers: strategies, achievements and future challenges. Adv. Drug Del. Rev., 57, 1553-1555.
  3. Bernkop-Schnürch, A. (2005). Mucoadhesive systems in oral drug delivery. Drug Discovery Today: Technologies, 2, 83-87.
  4. Bernkop-Schnürch, A. and Greimel, A. (2005). Thiomers: The next generation of mucoadhesive polymers. Am. J. Drug. Deliv., 3, 141-154.
  5. Bernkop-Schnürch, A., Pinter, Y., Guggi, D., Kahlbacher, H., Schöffmann, G., Schuh, M., Schmerold, I., Del Curto, M.D., D'Antonio, M., Esposito, P. and Huck, Ch. (2005). The use of thiolated polymers as carrier matrix in oral peptide delivery - Proof of concept. J. Control. Rel., 106, 26-33.
  6. Grabovac, V., Guggi, D., and Bernkop-Schnürch, A. (2005). Comparison of the mucoadhesive properties of various polymers. Adv. Drug Del. Rev., 57, 1713-1723.
  7. Guggi, D. and Bernkop-Schnürch, A. (2005). Improved paracellular uptake by the combination of different types of permeation enhancers. Int. J. Pharm., 288, 141-150.
  8. Imam, M.E. and Bernkop-Schnürch, A. (2005). Controlled drug delivery systems based on thiolated chitosan microspheres. Drug Dev. Ind. Pharm., 31, 557-565.
  9. Kafedjiiski, K., Föger, F., Werle, M. and Bernkop-Schnürch, A. (2005). Synthesis and in vitro evaluation of a novel chitosan-glutathione conjugate. Pharm. Res., 22, 1480-1488.
  10. Kafedjiiski, K., Krauland, A.H., Hoffer, M.H. and Bernkop-Schnürch, A. (2005). Synthesis and in vitro evaluation of a novel thiolated chitosan. Biomaterials, 26, 819-826.
  11. Kafedjiiski, K., Werle, M., Föger, F. and Bernkop-Schnürch, A. (2005). Synthesis and in vitro characterization of a novel poly(acrylic acid)-glutathione conjugate. J. Drug Del. Sci.Tech., 15, 411-417.
  12. Krauland, A., Hoffer, M.H., and Bernkop-Schnürch, A. (2005). Viscoelastic properties of a new in situ gelling thiolated chitosan conjugate. Drug Dev. Ind. Pharm., 31, 885-893.
  13. Langoth, N. and Bernkop-Schnürch, A. (2005). The use of multifunctional polymers as auxiliary agents in non-invasive peptide delivery. Am. Pharm. Rev., 8, 80-84.
  14. Langoth, N., Bernkop-Schnürch, A. and Kurka, P. (2005). The inhibitory effect of glutathione towards buccal enzymatic degradation of therapeutic peptides (leu-enkephalin, luteinizing hormone-releasing hormone and pituitary adenylate cyclase activating peptide). J. Drug Del. Sci.Tech., 15, 435-438.
  15. Langoth, N., Bernkop-Schnürch, A. and Kurka, P. (2005). In vitro evaluation of various buccal permeation enhancing systems for PACAP (pituitary adenylate cyclase-activating polypeptide). Pharm. Res., 22, 2045-2050.
  16. Langoth, N., Kalbe, J. and Bernkop-Schnürch, A. (2005). Development of a mucoadhesive and permeation enhancing buccal delivery system for PACAP (pituitary adenylate cyclase-activating polypeptide). Int. J. Pharm., 296, 103-111.
  17. Maculotti, K., Genta, I., Perugini, P., Imam,M., Bernkop-Schnürch, A. and Pavanetto, F. (2005). Preparation and in vitro evaluation of thiolated chitosan microparticles. J. Microencap., 22, 459-470.
  18. Schmitz, T., Leitner, V., Bernkop-Schnürch, A. (2005). Oral heparin delivery: Design and in vivo evaluation of a stomach-targeted mucoadhesive delivery system. J. Pharm. Sci., 94, 966-973.
  19. Werle, M., Schmitz T., Wentzel A., Kolmar H. and Bernkop-Schnürch A. (2005). In vitro evaluation of the enzymatic stability and permeation behaviour of microbodies: novel carriers for oral peptide drug delivery? Pharmacia, 52, 126-127.
  1. Bernkop-Schnürch*, A., Clausen, A.E. and Guggi, D. (2004). The use of auxiliary agents to improve the mucosal uptake of peptides. Med. Chem. Rev., 1, 1-10.
  2. Bernkop-Schnürch*, A., Guggi, D., and Pinter, Y.  (2004).  Thiolated chitosans: development and in vivo evaluation of a mucoadhesive permeation enhancing oral drug delivery system. J. Control. Rel., 94, 177-186.
  3. Bernkop-Schnürch*, A., Hoffer, M. and Kafedjiiski, K. (2004). Thiomers for oral delivery of hydrophilic macromolecular drugs. Expert Opinion Drug Deliv., 1, 87-98.
  4. Bernkop-Schnürch*, A., Hornof, M.D. and Guggi, D.  (2004).  Thiolated Chitosans.  Eur. J. Pharm. Biopharm., 57, 9-17.
  5. Bernkop-Schnürch*, A., König, V., Leitner, V., Krauland, A. and Brodnik, I. (2004).  Preparation and characterisation of thiolated poly(methacrylic acid) - starch compositions.  Eur. J. Pharm. Biopharm., 57, 219-224.
  6. Bernkop-Schnürch*, A., Krauland, A.H., Leitner, V.M. and Palmberger, Th. (2004).  Thiomers: potential excipients for non-invasive peptide delivery systems.  Eur. J. Pharm. Biopharm., 58, 253-263.
  7. Bernkop-Schnürch*, A., Leitner, V., and Moser, V. (2004).  Synthesis and in vitro characterisation of a Poly(Acrylic Acid)-Homocysteine Conjugate.  Drug Dev. Ind. Pharm., 30, 1-8.
  8. Bernkop-Schnürch*, A., Reich-Rohrwig, E., Marschütz, M., Schuhbauer H. and Kratzel, M. (2004).  Development of a Sustained Release Dosage Form for alpha-Lipoic Acid. II. Evaluation in Human Volunteers. Drug Dev. Ind. Pharm., 30, 35-42.
  9. Bernkop-Schnürch*, A., Schuhbauer H., Clausen, A.E. and Hanel, R. (2004).  Development of a Sustained Release Dosage Form for alpha-Lipoic Acid. I. Design and in Vitro Evaluation.  Drug Dev. Ind. Pharm., 30, 27-34.
  10. Caliceti*, P. Salmaso, S., Walker, G. and Bernkop-Schnürch, A.  (2004).  Development and In Vivo Evaluation of an Oral Insulin-PEG Delivery System.  Eur. J. Pharm. Sci., 22, 315-323.
  11. Griesser*, U.J., Weigand, D., Rollinger, J., Haddow, M. and Gstrein, E. (2004). The Crystal Polymorphs of Metazachlor: Identification and Thermodynamic Stability. J. Therm. Anal. Cal. 77, 511-522.
  12. Guggi, D., Langoth, N., Hoffer, M.H., Wirth, M. and Bernkop-Schnürch, A.  (2004).  Comparative evaluation of cytotoxicity of a glucosamine-TBA conjugate and a chitosan-TBA conjugate  Int. J. Pharm., 278, 353-360. 
  13. Guggi, D., Marschütz, M.K., and Bernkop-Schnürch*, A. (2004).  Matrix tablets based on thiolated poly(acrylic acid): pH-dependent variation in disintegration and mucoadhesion. Int. J. Pharm., 274, 97-105.
  14. Kafedjiiski*, K.  (2004).  Multifunctional Polymeric Excipients in Non-Invasive Delivery of Hydrophilic Macromolecular Drugs: The Thiomer-Technology. The Drug Del. Comp. Rep., 2004, 47-50.
  15. Krauland, A. and Bernkop-Schnürch*, A. (2004).  Thiomers: Development and in vitro evaluation of a peroral microparticulate peptide delivery system. Eur. J. Pharm. Biopharm., 57, 181-187.
  16. Krauland, A., Guggi, D. and Bernkop-Schnürch*, A. (2004).  Oral insulin delivery: The potential of thiolated chitosan-insulin tablets on non-diabetic rats.  J. Control. Rel., 95, 547-555.
  17. Leitner, V., Guggi, D. and Bernkop-Schnürch*, A. (2004).  Thiomers in Noninvasive Polypeptide Delivery: In Vitro and In Vivo Characterization of a Polycarbophil-Cysteine/Glutathione Gel Formulation for Human Growth Hormone  J. Pharm. Sci., 93, 1682-1691.
  18. Leitner, V.M. and Bernkop-Schnürch*, A. (2004). Polymer-enzyme inhibitor conjugates: influence of the molecular mass on the inhibition of membrane-bound aminopeptidase N activity  J. Drug. Del. Sci.Tech., 14, 495-498. 
  19. Leitner, V.M., Guggi, D., Krauland, A.H. and Bernkop-Schnürch*, A. (2004). Nasal Delivery of human growth hormone: in vitro and in vivo evaluation of a thiomer/glutathione microparticulate delivery system. J. Control. Rel., 100, 87-95.
  20. Roldo, M., Hornof, M., Caliceti, P. and Bernkop-Schnürch*, A.  (2004).  Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: Synthesis and in vitro evaluation. Eur. J. Pharm. Biopharm., 57, 115-121.
  21. Schmidt, A.C., Niederwanger, V., and Griesser*, U.J. (2004): Solid state forms of Prilocaine Hydrochloride. Crystal Polymorphism of Local Anaesthetic Drugs, Part II. J. Therm. Anal. Cal., 77, 639-652.
  1. Bernkop-Schnürch*, A., Egger, C. Elhassan, I.M. and Krauland, A. (2003).  Preparation and in vitro characterization of poly(acrylic acid)-cysteine mircoparticles.  J. Control. Rel., 93, 29-38.
  2. Bernkop-Schnürch*, A., Hornof, M. and Zoidl, T. (2003).  Thiolated polymers – thiomers: modification of chitosan with 2-iminothiolane.  Int. J. Pharm., 260, 229-237.
  3. Bernkop-Schnürch*, A., Telsnig. J. and Hornof, M. (2003).  Development and In Vitro Evaluation of a Mucoadhesive Oral Delivery System for Antisense Oligonucleotides.  Sci. Pharm., 71, 165-177.
  4. Guggi, D., and Bernkop-Schnürch*, A. (2003).  In vitro evaluation of polymeric excipients protecting calcitonin against degradation by intestinal serine proteases.  Int. J. Pharm., 252, 187-196.
  5. Guggi, D., Kast, C.E., and Bernkop-Schnürch*, A. (2003).  In vivo evaluation of an oral salmon calcitonin-delivery system based on a thiolated chitosan carrier matrix.  Pharm. Res., 20, 1989-1994.
  6. Guggi, D., Krauland, A.H., and Bernkop-Schnürch*, A. (2003).  Systemic peptide delivery via the stomach: in vivo evaluation of an oral dosage form for salmon calcitonin.  J. Control. Rel., 92, 125-135.
  7. Hornof, M.D., Kast, C.E., and Bernkop-Schnürch*, A. (2003).  In vitro evaluation of the viscoelastic properties of chitosan - thioglycolic acid conjugates.  Eur. J. Pharm. Biopharm., 55, 185-190.
  8. Hornof, M.D., Weyenberg, W., Ludwig, A., and Bernkop–Schnürch*, A. (2003).  A mucoadhesive ocular insert: Development and in vivo evaluation in humans.  J. Control. Rel., 89, 419-428.
  9. Imam, M.E., Hornof, M., Valenta, C., and Bernkop-Schnürch*, A.  (2003).  Evidence for the interpenetration of mucoadhesive polymers into the mucus gel layer.  STP pharma, 13, 171-176.
  10. Kast, C.E., Frick, W., Losert, U. and Bernkop-Schnürch*, A.  (2003).  Chitosan-thioglycolic acid conjugate: A new scaffold material for tissue engineering?  Int. J. Pharm., 256 (1-2), 183-189.
  11. Kast, C.E., Guggi, D., Langoth, N. and Bernkop-Schnürch*, A.  (2003).  Development and in vivo evaluation of an oral delivery system for low molecular weight heparin based on thiolated polycarbophil.  Pharm. Res., 20, 931-936.
  12. Krauland, A., Leitner, V. M. and Bernkop-Schnürch*, A. (2003).  Improvement in the in situ gelling properties of deacetylated gellan gum by the immobilization of thiol groups.  J. Pharm. Sci., 92, 1234-1241.
  13. Langoth, N., Kalbe, J. and Bernkop-Schnürch*, A. (2003).  Development of buccal drug delivery systems based on a thiolated polymer.  Int. J. Pharm., 252, 141-148.
  14. Leitner, V., Marschütz, M., and Bernkop-Schnürch*, A. (2003).  Mucoadhesive and cohesive properties of poly(acrylic acid)-cysteine conjugates with regard to their molecular mass.  Eur. J. Pharm. Sci., 18, 89-96.
  15. Leitner, V., Walker, G.F., and Bernkop-Schnürch*, A. (2003).  Thiolated polymers: Evidence for the formation of disulphide bonds with mucus glycoproteins.  Eur. J. Pharm. Biopharm., 56, 207-214.
  16. Schmidt, A.C., Senfter, N. and Griesser*, U.J. (2003). Crystal Polymorphism of Local Anaesthetic Drugs, Part I: Pramocaine Base in Comparison with Pramocaine Hydrochloride. J. Therm. Anal. Cal., 73, 397-408.
  17. Te*, R.L., Griesser, U.J., Morris, K.R., Byrn, S.R., and Stowell, J.G. (2003). X-ray Diffraction and Solid-State NMR Investigation of the Single-Crystal to Single-Crystal Dehydration of Thiamine Hydrochloride Monohydrate. Crystal Growth and Design, 3, 997-1004.
  1. Bernkop-Schnürch*, A., Hornof, M.D., Kast, C.E. and Langoth N. (2002). Thiolated polymers: Stability of thiol moieties under different storage conditions.  Sci. Pharm., 70, 331-339.
  2. Clausen, A.E., Kast, C.E. and Bernkop-Schnürch*, A. (2002).  The role of glutathione in the permeation enhancing effect of thiolated polymers.  Pharm. Res., 19, 602-608.
  3. Hornof M.D. and Bernkop-Schnürch*, A.  (2002).  In vitro evaluation of the permeation enhancing effect of polycarbophil - cysteine conjugates on the cornea of rabbits.  J. Pharm. Sci., 91, 2588-2592.
  4. Kast, C.E. and Bernkop-Schnürch*, A.  (2002).  Influence of the molecular mass on the permeation enhancing effect of different poly(acrylates).  STP pharma, 12, 351-356.
  5. Kast, C.E., and Bernkop-Schnürch*, A.  (2002).  Polymer-cystamine conjugates: new mucoadhesive excipients for drug delivery?  Int. J. Pharm., 234, 91-99.
  6. Kast, C.E., Valenta*, C., Leopold, M. and Bernkop-Schnürch, A.  (2002).  Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clotrimazole.  J. Control. Rel., 81, 347-354.
  7. Marschütz, M.K., and Bernkop-Schnürch*, A. (2002).  Thiolated polymers: Advance in mucoadhesion by use of in-situ crosslinking poly(acrylic acid)-cysteine conjugates.  Eur. J. Pharm. Sci., 15, 387-394.
  8. Marschütz, M.K., Zauner, W., Mattner, F., Otava, A., Buschle, M. and Bernkop-Schnürch*, A. (2002).  Improvement of the enzymatic stability of a cytotoxic T-lymphocyte epitope model peptide for its oral administration.  Peptides, 23, 1727-1733.
  9. Valenta*, C., Marschütz, M., Egyed, Ch., and Bernkop-Schnürch, A. (2002).  Evaluation of the inhibitory effect of thiolated poly(acrylates) on vaginal membrane bound aminopeptidase N.  J. Pharm. Pharmacol., 54, 603-610.
  10. Walker, G.F., Langoth, N., and Bernkop-Schnürch*, A.  (2002).  Peptidase activity on the surface of the porcine buccal mucosa.  Int. J. Pharm., 233, 141-147.
  11. Schlocker* W. Mányi A., Semenitz E.: Qualität magistral hergestellter niedrig dosierter Phenobarbitalkapseln. Krankenhauspharmazie; 23:392-6, 2002.
  12. Schmidt* A.C., Griesser U.J., Brehmer T., Harris R.K., and King A. (2002): Conformational Polymorphism of the Local Anaesthetic Drug Oxybuprocaine Hydrochloride. Acta Crystallogr. A58, C140.
  1. Bernkop-Schnürch*, A. and Hopf, Th.E.  (2001).  Synthesis and In vitro evaluation of chitosan-thioglycolic acid conjugates.  Sci. Pharm., 69, 109-118.
  2. Bernkop-Schnürch*, A., Clausen, A.E., and Hnatyszyn, M. (2001).  Thiolated Polymers: Synthesis and in vitro evaluation of polymer-cysteamine conjugates.  Int. J. Pharm., 226, 185-194.
  3. Bernkop-Schnürch*, A., Kast, C.E., and Richter, M.F. (2001).  Improvement in the mucoadhesive properties of alginate by the covalent attachment of cysteine.  J. Control. Rel., 71, 277-285.
  4. Bernkop-Schnürch*, A., Zarti, H., and Walker, G.F. (2001).  Thiolation of polycarbophil enhances its inhibition of soluble and intestinal brush border membrane bound aminopeptidase N.  J. Pharm. Sci., 90, 1907-1914.
  5. Clausen, A.E., and Bernkop-Schnürch*, A. (2001).  Thiolated Carboxymethylcellulose: In vitro evaluation of its permeation enhancing effect on peptide drugs.  Eur. J. Pharm. Biopharm., 51, 25-32.
  6. Clausen, A.E., and Bernkop-Schnürch*, A. (2001).  Development and in Vitro Evaluation of a Peptide Drug Delivery System Based on Thiolated Polycarbophil.  Pharm. Ind., 63, 312-317.
  7. Clausen, A.E., and Bernkop-Schnürch*, A. (2001).  Direct compressible polymethacrylic acid-starch compositions for site specific drug delivery.  J. Control. Rel., 75, 93-102.
  8. Kast, C.E., and Bernkop-Schnürch*, A.  (2001).  Thiolated polymers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates.  Biomaterials, 22, 2345 - 2352.
  9. Marschütz, M.K., Puttipipatkhachorn, S., and Bernkop-Schnürch*, A. (2001).  Design and in vitro evaluation of a mucoadhesive oral delivery system for a model (poly)peptide antigen.  Pharmazie, 56, 724-729.
  10. Marschütz, M.K., Veronese, F.M., and Bernkop-Schnürch*, A. (2001).  Influence of the spacer on the inhibitory effect of different polycarbophil-protease inhibitor conjugates.  Eur. J. Pharm. Biopharm., 52, 137-44.
  11. Valenta*, C., Kast, E.C., Harich, I., and Bernkop-Schnürch, A. (2001).  Development and in vitro Evaluation of a Mucoadhesive Vaginal Delivery System for Progesterone.  J. Control. Rel., 77, 323-332.
  12. Valenta*, C., Walzer, A., Clausen, A.E., and Bernkop-Schnürch, A.  (2001).  Thiolated polymers: development and evaluation of transdermal delivery systems for progesterone.  Pharm. Res., 18, 211-216.
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