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SFB-F44 - Cell signaling in chronic CNS disorders

SFB Publications


2019


Kaplan MM, Flucher BE (2019) Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction Sci Rep. 9(1):18450. doi: 10.1038/s41598-019-54900-w


Grimm C, Hillen HS, Bedenk K, Bartuli J, Neyer S, Zhang Q, Hüttenhofer A, Erlacher M, Dienemann C, Schlosser A, Urlaub H, Böttcher B, Szalay AA, Cramer P, Fischer U (2019) Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes Cell. 2019 Dec 12 doi: 10.1016/j.cell.2019.11.024


Grzegorz Kreiner, Aynur Sönmez, Birgit Liss and Rosanna Parlato (2019) Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases. Front. Mol. Neurosci. 2019 12:106 doi: 10.3389/fnmol.2019.00106


Martin Kiechle, Bjoern von Einem, Lennart Höfs, Patrizia Voehringer, Veselin Grozdanov, Daniel Markx, Rosanna Parlato, Diana Wiesner, Benjamin Mayer, Olena Sakk, Bernd Baumann, Soeren Lukassen, Birgit Liss, Arif B.Ekici, Albert C.Ludolph, Paul Walther, Boris Ferger, Pamela J. McLean, Björn H. Falkenburger, Jochen H. Weishaupt, Karin M. Danzer (2019) In Vivo Protein Complementation Demonstrates Presynaptic a-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species. Cell Reports 2019 Nov 29:2862-2874.e9 doi: doi.org/10.1016/j.celrep.2019.10.089


Carsten Simons, Julia Benkert, Nora Deuter, Christina Poetschke, Olaf Pongs, Toni Schneider, Johanna Duda and Birgit Liss (2019) NCS-1 Deficiency Affects mRNA Levels of Genes Involved in Regulation of ATP Synthesis and Mitochondrial Stress in Highly Vulnerable Substantia nigra Dopaminergic Neurons. Front. Mol. Neurosci. 2019 Nov 12:252. doi: 10.3389/fnmol.2019.00252


Julia Benkert, Simon Hess, Shoumik Roy, Dayne Beccano-Kelly, Nicole Wiederspohn, Johanna Duda, Carsten Simons, Komal Patil, Aisylu Gaifullina, Nadja Mannal, Elena Dragicevic, Desirée Spaich, Sonja Müller, Julia Nemeth, Helene Hollmann, Nora Deuter, Yassine Mousba, Christian Kubisch, Christina Poetschke, Joerg Striessnig, Olaf Pongs, Toni Schneider, Richard Wade-Martins, Sandip Patel, Rosanna Parlato1, Tobias Frank, Peter Kloppenburg & Birgit Liss (2019) Cav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson’s disease. Nat. Commun. 2019 10:5094 doi: 10.1038/s41467-019-12834-x


Porpora M, Sauchella S, Rinaldi L, Delle Donne R, Sepe M, Torres-Quesada O, Intartaglia D, Garbi C, Insabato L, Santoriello M, Bachmann V, Synofzik M, Lindner H, Ivan C, Stefan E, Feliciello A. Counterregulation of cAMP-directed kinase activities controls ciliogenesis. Nat. Commun. 2018 Mar 26;9(1):1224. doi: 10.1038/s41467-018-03643-9


Röck R, Mayrhofer JE, Torres-Quesada O, Enzler F, Raffeiner A, Raffeiner P, Feichtner A, Huber RG, Koide S, Taylor SS, Troppmair J, Stefan E*. (2019) BRAF inhibitors promote intermediate BRAF(V600E) conformations. Science Advances 2019 Aug 14;5(8):eaav8463. doi: 10.1126/sciadv.aav8463


Calorio C, Gavello D, Guarina L, Salio C, Sassoè-Pognetto M, Riganti C, Bianchi FT, Hofer NT, Tuluc P, Obermair GJ, Defilippi P, Balzac F, Turco E, Bett GC, Rasmusson RL, Carbone E (2019) Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers. J Physiol. Jan 10. doi: 10.1113/JP277487. [Epub ahead of print] PubMed PMID: 30629744


Cera I, Whitton L, Donohoe G. Morris DW, Dechant G, Apostolova G (2019) Genes encoding SATB2-interacting proteins in adult cerebral cortex contribute to human cognitive ability. PLOS Genetics (in press, DOI: 10.1371/journal.pgen.1007890 


Geisler S, Schöpf CL  Stanika R, Kalb M, Campiglio M, Repetto D, Traxler L, Missler M, Obermair GJ (2019) Presynaptic α(2)δ-2 calcium channel subunits regulate postsynaptic GABA(A)-receptor abundance and axonal wiring. J Neurosci. Jan 25. pii: 2234-18. doi: 10.1523/JNEUROSCI.2234-18.2019. [Epub ahead of print] PubMed PMID: 30683685


Liss B, Striessnig J (2019) The Potential of L-Type Calcium Channels as a Drug Target for Neuroprotective Therapy in Parkinson’s Disease. Annu. Rev. Pharmacol. Toxicol. 59, 263–289. https://doi.org/10.1146/annurev-pharmtox-010818-021214


Jin J, Bhatti DL, Lee KW, Medrihan L, Cheng J, Wie J, Zhong P, Yan Z, Kooiker C, Song C, Ahn JH, Obermair GJ, Lee A, Gresack J, Greengard P, Kim Y  (2019) Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior. Mol Psychiatry. Feb 13. doi: 10.1038/s41380-019-0371-y. [Epub ahead of print] PubMed PMID: 30760886.

 

 

 

 

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