Selected Publications
Selected Publications for "Transcriptional control of mesoderm patterning in zebrafish"
Fischer P, Chen H, Pacho F, Rieder D, Kimmel RA, Meyer D. FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical Regulation. BMC Biology 2019 Jul 30;17(1):61. DOI: 10.1186/s12915-019-0683-z. Pubmed
Chen, H.; Babino, D; Schoenbichler, SA.; Arkhipova, V; Töchterle, S; Martin, F; Huck, CW; von Lintig, J; Meyer, D (2015): Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7.
In: PLoS One 10/11, S. e0143825. (DOI) (Weblink)
Dumortier, JG, Martin, S., Meyer, D., Rosa, FM, David, NB (2012) Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts. Proceedings of the National Academy of Sciences, PNAS, 0027-8424, DOI: 10.1073/pnas.1205870109 Pubmed
Epting, D., Vorwerk, S., Hagemann, A., Meyer, D. (2007) Expression of rasgef1b in zebrafish. Gene Expr Patterns 7:389-95
Keegan, BR., Meyer, D., Yelon, D. (2004) Organization of cardiac chamber progenitors in the zebrafish blastula. Development 131, 3081-91
Trinh, L., Meyer, D. and Stainier, D. Y. (2003) The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish. Development 130, 4989-98
Pogoda, H. M. and Meyer, D. (2002) Zebrafish Smad7 is regulated by Smad3b and BMP signals. Dev Dyn 224, 334-49
Pogoda, H. M. Solnica-Krezel, L., Driever, W., Meyer, D. (2002) The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of nodal signaling required for organizer formation. Curr Biol. 10:1041-9
Selected Publications for "Control of Pancreas Formation and Regeneration"
Temocin, O.; Regele, D.; Sathianathan, M.; Überbacher, C.; Hartl, M.; Edenhofer, F.; Meyer, D. (2021): Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet. In Stem Cell Research 56, Nr. 102522 Epub 2021 Sep2 Doi: 10.1016/j.scr.2021.102522. Pubmed
Emfinger CH, Lőrincz R, Wang Y, York NW, Singareddy SS, Ikle JM, Tryon RC, McClenaghan C, Shyr ZA, Huang Y, Reissaus CA, Meyer D, Piston DW, Hyrc K, Remedi MS, Nichols CG. Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets. Physiological Reports 2019 Jun;7(11):e14101. DOI: 10.14814/phy2.14101. Pubmed
Lorincz R, Emfinger CH, Walcher A, Giolai M, Krautgasser C, Remedi MS, Nichols CG, Meyer D. In vivo monitoring of intracellular Ca2+ dynamics in the pancreatic β-cells of zebrafish Embryos.In Islets 2018;10(6):221-238. (DOI) 2018.1540234. Epub 2018 Dec 6. Pubmed
Freudenblum J, Iglesias JA, Hermann M, Walsen T, Wilfinger A, Meyer D, Kimmel RA. In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis. In Development 2018 Feb 8:145(3). (DOI) Pubmed
Facchinello, N; Tarifeño-Saldivia, E; Grisan, E; Schiavone, M; Peron, M; Mongera, A; Ek, O; Schmitner, N; Meyer, D; Peers, B; Tiso, N; Argenton, F; (2017) Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and Regeneration. In Scientific Reports 2017; 7: 9605. Published online 2017 Aug 29. (DOI) Pubmed
Schmitner, Nicole; Kohno, Kenji; Meyer, Dirk (2017) Ptf1a+, ela3l− cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae. In Disease Models & Mechanisms 2017 Jan 30. pii: dmm.026633. (DOI) Pubmed [epub ahead of print]
Li, J; Casteels, T; Frogne,T; Ingvorsen, C; Honoré, C; Courtney, M; Huber, KV; Schmitner, N; Kimmel, RA; Romanov, RA; Sturtzel, C; Lardeau, CH7; Klughammer, J; Farlik, M; Sdelci, S; Vieira, A; Avolio, F; Briand, F; Baburin, I; Májek, P; Pauler, FM; Penz, T; Stukalov, A; Gridling, M; Parapatics, K; Barbieux, C; Berishvili, E; Spittler, A; Colinge, J: Bennett, KL; Hering, S; Sulpice, T; Bock, C; Distel, M; Harkany, T; Meyer, D; Superti-Furga, G; Collombat, P; Hecksher-Sørensen, J; Kubicek S (2017) Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity. In CELL 2017 Jan 12;168(1-2):86-100.e15. Epub 2016 Dec 1. (DOI) Pubmed
Kimmel, R.A.; Meyer, D. (2016) Zebrafish Pancreas as a Model for Development and Disease. Methods in Cell Biology, available online 17 March 2016. doi:10.1016/bs.mcb.2016.02.009 . Pubmed
Kimmel, R.A., Dobler, S., Schmitner, N., Walsen, T., Freudenblum, J., and Meyer, D. (2015). Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment. Sci. Rep. 5, 14241 Pubmed
Liu, M., Schmitner, N., Sandrian, M.G., Zabihian, B., Hermann, B., Salvenmoser, W., Meyer, D., Drexler, W., (2013) In vivo three dimensional dual wavelength photoacoustic tomography imaging of the far red fluorescent protein E2-Crimson expressed in adult zebrafish, Biomedical Optics Express, Vol. 4, Issue 10, pp. 1846-1855. doi: 10.1364/BOE.4.001846. OpticsInfoBase
Wurzinger G., Nuster R., Schmitner N., Gratt S., Meyer D., Paltauf G. (2013) Simultaneous three-dimensional photoacoustic and laser-ultrasound tomography. Biomed Opt Express. 2013 Jul 19;4(8):1380-9. doi: 10.1364/BOE.4.001380. Pubmed
Nuster R, Schmitner N, Wurzinger G, Gratt S, Salvenmoser W, Meyer D, Paltauf G. (2013) Hybrid photoacoustic and ultrasound section imaging with optical ultrasound detection. J Biophotonics. 2013 May 5. DOI: 10.1002/jbio.201200223. [Epub ahead of print]. PMID: 23650129 PubMed
Wilfinger, A., Arkhipova, V., Meyer D., Cell type and tissue specific function of islet genes in zebrafish pancreas development.Dev. Biol. (2013) Volume 378, Issue 1, 1 June 2013, Pages 25–37. doi: 10.1016/j.ydbio.2013.03.009. Science direct
Arkhipova V., Wendik B., Devos N., Ek O., Peers B., Meyer D. (2012) Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish. Dev Biol. 2012 May 1;365(1):290-302. Epub 2012 Mar 9. DOI: 101016, Pubmed
Nuster R., Gratt S., Passler K., Meyer D., and Paltauf G., "Photoacoustic section imaging using an elliptical acoustic mirror and optical detection", J. Biomed. Opt. 17, 030503 (2012), DOI:10.1117/1.JBO.17.3.030503. SPIE Digital Library
Kimmel RA, Onder L, Wilfinger A, Ellertsdottir E, Meyer D. (2011) Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish. BMC Biol. 2011 Oct 31;9:75. Pubmed
Untergasser, G., Martowicz, A., Hermann, M., Töchterle, S., Meyer, D. (2011) Distinct expression patterns of dickkopf genes during late embryonic development of Danio rerio. Gene Expr Patterns. 2011 Aug 26. Pubmed
Kimmel, R., Meyer, D. (2010) Molecular regulation of pancreas development in zebrafish. Methods Cell Biol 100, 261-80 PubMed
Wendik, B., Maier, E., Meyer, D. (2004) Zebrafish mnx genes in endocrine and exocrine pancreas formation Dev. Biol. 268, 372-83 PubMed
Zecchin, E. Mavropoulos, A., Devos, N.,. Filippi, A., Tiso, N., Meyer, D., Peers, B., Bortolussi, M., Argenton, F. (2004) Evolutionary conserved role of ptf1a in the exocrine pancreatic fate. Dev. Biol. 268, 174-84. PubMed
Gnugge, L., Meyer, D. and Driever, W. (2004) Pancreas development in zebrafish. Methods Cell Biol 76, 531. PubMed
Selected Publications for "Effects of diabetes related-genes on beta cell function and organism physiology"
Schmitner, N., Recheis, C., Thönig, J., Kimmel, R.A. (2021) Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia. Cells, 10, 3265. FEBS Letters Volume 597, Issue 2; January 2023; Pages 262-275. https://doi.org/10.3390/cells10113265
Ali Z, Zang J, Lagali N, Schmitner N, Salvenmoser W, Mukwaya A, Neuhauss S, Jensen L and Kimmel RA. Photoreceptor degeneration accompanies vascular changes in a zebrafish model of diabetic retinopathy. Investigative Ophthalmology & Visual Science. February 2020, Vol.61, 43. doi:https://doi.org/10.1167/iovs.61.2.43
Emfinger CH, Lőrincz R, Wang Y, York NW, Singareddy SS, Ikle JM, Tryon RC, McClenaghan C, Shyr ZA, Huang Y, Reissaus CA, Meyer D, Piston DW, Hyrc K, Remedi MS, Nichols CG. Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets. Physiological Reports 2019 Jun;7(11):e14101. 10.14814/phy2.14101. Pubmed
Lorincz R, Emfinger CH, Walcher A, Giolai M, Krautgasser C, Remedi MS, Nichols CG, Meyer D. In vivo monitoring of intracellular Ca2+ dynamics in the pancreatic β-cells of zebrafish Embryos.In Islets 2018;10(6):221-238. (DOI) 2018.1540234. Epub 2018 Dec 6. Pubmed
Facchinello, N; Tarifeño-Saldivia, E; Grisan, E; Schiavone, M; Peron, M; Mongera, A; Ek, O; Schmitner, N; Meyer, D; Peers, B; Tiso, N; Argenton, F; (2017) Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and Regeneration. In Scientific Reports 2017; 7: 9605. Published online 2017 Aug 29. (DOI) Pubmed
Kimmel, R.A.; Meyer, D. (2016) Zebrafish Pancreas as a Model for Development and Disease. Methods in Cell Biology, available online 17 March 2016. doi:10.1016/bs.mcb.2016.02.009 . Pubmed
Kimmel, R.A., Dobler, S., Schmitner, N., Walsen, T., Freudenblum, J., and Meyer, D. (2015). Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment. Sci. Rep. 5, 14241 Pubmed (doi: 10.1038/srep14241 ) (https://www.nature.com/articles/srep14241)