Mostafa ALILOU, MSc., PhD
Postdoctoral Researcher
Contact
Institute of Pharmacy/Pharmacognosy
University of Innsbruck
Center for Chemistry and Biomedicine
Innrain 80 - 82/IV
Room: L.04.062
6020 Innsbruck / Austria
Phone: +43 512 507 - 58419
Email: mostafa.alilou@uibk.ac.at
Research interests
- Isolation and identification of natural products from medicinal plants and microorganisms such as endophytes (bacteria and fungi) for targeting various aliments including cancer, inflammation, tropical diseases, infections
- Application of silent genes activation methods for expanding the chemical space of microorganisms
- Determination of absolute configuration of chiral natural products using chiroptical methods including electronic circular dichroism (ECD) and vibrational circular dichroism (VCD)
- Structure elucidation of Natural Products using Computer Assisted Structure Elucidation methods (CASE)
Publications
2021
Orfanoudaki, M.; Hartmann, A.;Alilou, M.; Mehic, N.; Kwiatkowski, M.; Jöhrer, K.; Nguyen Ngoc, H.; Hensel, A.; Greil, R.; Ganzera, M. Cytotoxic Compounds of Two Demosponges (Aplysina aerophoba and Spongia sp.) from the Aegean Sea. Biomolecules 2021, 11 (5), 723.
“Tran, T. V. A., Alilou, M., Zhigang, R.,”Simona, P., Schwaiger, S., Christian, K., Temmel, V., Carsten, G., Paul, M. J., Rossella, B., Christina, W., Silke, R., Waltenberger, B., Tran, H., Antonietta, R., Stuppner, H., Wertz, O., Koeberle, A. From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution.Acta Pharm. Sin. B.2021, 11 (6), 1629-1647.
Enayati, A., Salehi, A.,Alilou, M., Stuppner, H., Mirzaei, H., Omraninava, A., Khori, V., Yassa, N. Six new triterpenoids from the root of Potentilla reptans and their cardioprotective effects in silico. Nat. Prod. Res,2021, 1-9.
Soroury, S.,Alilou, M., Gelbrich, T. et al. Unusual derivatives from Hypericum scabrum.Sci Rep2020,10, 22181.
Hafez Goran, S.; Firuzi, O.; Asadollahi, M.; Stuppner, H.;Alilou, M.; Jassbi, A. R. Dammarane-type triterpenoid saponins from Salvia russellii Benth.Phytochmistry2021,184, 112653.
2020
Alilou, M.; Marzocco, S.; Hofer, D.; Rapa, S. F.; Asadpour, R.; Schwaiger, S.; Troppmair, J.; Stuppner, H. New Labdane-type Diterpenes from Aerial Parts ofRydingia persica- Absolute Configuration and Protective Effect on LPS-Induced Inflammation in Keratinocytes. J.Nat. Prod.2020,83(8), 2456-2468.
Pesyan, N. N.; Rashinejad, H.; Esmaeili, M. A.; Safari, E.; Tunc, T.;Alilou, M.; Safavi-Sohi, R.; Şahin, E. 4-Methyl morpholinium bis-(thio)barbiturates: Synthesis, structure, Anticancer evaluation, and CoMFA study.J. Chin. Chem. Soc.2020,67(9), 1679−1695.
Hasanpour, Z.; Salehi, P.; Barajanian, M.; Esmaeili, M. A.;Alilou, M.; Mohebbi, M. Semi-Synthesis of New 1,2,3-Triazole Derivatives of 9-Bromonoscapine and their Anticancer Activities.Iranian Journal of Pharmaceutical Research,2020 (in press).
Alilou, M.; Dibwe, D. F.; Schwaiger, S.; Khodami, M.; Troppmair, J.; Awale, S.; Stuppner, H. Antiausterity Activity of Secondary Metabolites from the Roots ofFerula hezarlalehzaricaagainst the PANC-1 Human Pancreatic Cancer Cell Line.J.Nat. Prod.2020,83, 1099-1106.
Alilou, M.; Marzocco, S.; Batooli, H.; Troppmair, J.; Schwaiger, S.; Stuppner, H. Unusual Secondary Metabolites of the Aerial Parts ofDionysia diapensiifolia(Primulaceae) and Their Anti-Inflammatory Activity.Biomolecules2020,10(3), 1–15.
Orfanoudaki, M. and Hartmann, A.;Alilou, M.; Gelbrich, T.; Plan-chenault, P.; Schinkovitz, A.; Richomme, P.; Hensel, A.; Ganzera, M. Absolute Configuration of Mycosporine-Like Amino Acids, Their Wound Healing Properties and In Vitro. Mar. Drugs2020,18, 35–51.
2019
Ngyuen Ngoc, H.;Alilou, M.; Stonig, M.; Nghiem, D. T.; Kim, L. T.; Gostner, J. M.; Stuppner, H.; Ganzera, M. Terpenoids from the Stems ofFissistigma polyanthoidesand Their Anti-Inflammatory Activity.J. Nat. Prod.2019,82, 2941–2952.
Pecio, Ł.;Alilou, M.; Kozachok, S.; Erdogan Orhan, I.; Eren, G.; Senol Deniz, F.S.; Stuppner, H.; Oleszek, W. Yuccalechins A–C from theYucca schidigeraRoezl ex Ortgies Bark: Elucidation of the Relative and Absolute Configurations of Three New Spirobiflavonoids and Their Cholinesterase Inhibitory Activities.Molecules2019,24, 4162–4186.
Karimzadeh, S. M.; Moridi, F.; Mahdi, A.; Mohammad, S.; Tabefam, M.;Alilou, M.; Stuppner, H. Perovskanol, a New Sesquiterpenoid with an Unprecedented Skeleton fromPerovskia abrotanoides.Nat.Prod. Res.2019, Nov. 1, 1–5.
2018
Pompermaier, L.; Heiss, E. H.;Alilou, M.; Mayr, F.; Monizi, M.; Lautenschlaeger, T.; Schuster, D.; Schwaiger, S.; Stuppner, H. Dihydrochalcone Glucosides from the Subaerial Parts ofThonningia sanguineaand Their in Vitro PTP1B Inhibitory Activities.J. Nat. Prod.2018,81(9), 2091–2100.
2017
Marzocco, S.; Adesso, S.;Alilou, M.; Stuppner, H.; Schwaiger, S. Anti-Inflammatory and Anti-Oxidant Potential of the Root Extract and Constituents ofDoronicum austriacum. Molecules2017,22(6), 1003–1016.
2015
Esmaeili, M. A.;Alilou, M.; Sonboli, A. Neuroprotective effects ofSalvia aristataAucher ex Benth. on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblastoma cells.Research Journal of Pharmacognosy (RJP), 2015,2, 17-26.
2014
Esmaeili, M. A.;Alilou, M.Naringenin Attenuates CCl4-Induced Hepatic Inflammation by the Activation of an Nrf2-Mediated Pathway in Rats. Clin. Exp.Pharmacol. Physiol.2014,41(6), 416–422.
Teaching activities
- Principals of phytochemical techniques, UE
- Bachelor´s Thesis in Pharmacy, PS
- Diploma- and Master Thesis in Pharmacy, UE, SE