Sonja STURM, Mag. pharm. Dr.

Publications (last five years)

Mayr, F., Sturm, S., Ganzera, M., Waltenberger, B., Martens, S., Schwaiger, S., Schuster, D., Stuppner, H. (2019). Mushroom Tyrosinase-based Enzyme Inhibition Assays Are Not Suitable for Bioactivity-Guided Fractionation of Extracts". J Nat Prod 82:136-147. DOI: 1021/acs.jnatprod.8b00847

Vieider, L., Romp, E., Kretzer, C., Schoenthaler, M., Taha, A., Temml, V., Sturm, S., Schuster, D., Werz, O., Garscha, U., Matuszczak, B. (2019). Synthesis, biological evaluation and structure-activity relationships of diflapolin derivatives as dual sEH/FLAP inhibitors". ACS Med Chem Lett 10(1):62-66. DOI: 1021/acsmedchemlett.8b00415

Spetea, M., Rief, S.B., Ben Haddou, T., Fink, M., Kristeva, E., Mittendorfer, H., Haas, S., Hummer, N., Follia, V., Guerrieri, E., Faheem Asim, M., Sturm, S., Schmidhammer, H. (2019). Synthesis, Biological and Structural Explorations of 6-Amino Acid Substituted Derivatives of 14-O-Methyloxymorphone, as Potent Mu/Delta Opioid Agonists and Peripherally Selective Antinociceptives. J Med Chem 62(2): 641-653. DOI: 1021/acs.jmedchem.8b01327

Moosmang, S., Pitscheider, M., Sturm, S.*, Seger, C., Tilg,V., Halabalaki, M., Stuppner, H. (2019). Metabolomic analysis—Addressing NMR and LC-MS related problems in human feces sample preparation. Clin Chim Acta 489:169-176. DOI:10.1016/j.cca.2017.10.029

McAlpine, J.B., Chen, S.N., Kutateladze, A., MacMillan, J.B., Appendino, G., Barison, A., Beniddir, M.A., Biavatti, M.W., Bluml, S., Boufridi, A., Butler, M.S., Capon, R.J., Choi, Y.H., Coppage, D., Crews, P., Crimmins, M.T., Csete, M., Dewapriya, P., Egan, J.M., Garson, M.J., Genta-Jouve, G., Gerwick, W.H., Gross, H., Harper, M.K, Hermanto, P., Hook, J.M., Hunter, L., Jeannerat, D., Ji N.Y., Johnson, T.A., Kingston, D.G.I., Koshino, H., Lee, H.W., Lewin, G., Li, J., Linington, R.G., Liu, M., McPhail, K.L., Molinski, T.F., Moore, B.S., Nam, J.W., Neupane, R.P., Niemitz, M., Nuzillard, J.M., Oberlies, N.H., Ocampos, F.M.M, Pan, G., Quinn, R.J., Reddy, D.S., Renault, J.H., Rivera-Chávez, J., Robien, W., Saunders, C.M., Schmidt, T.J., Seger, C., Shen, B., Steinbeck, C., Stuppner, H., Sturm, S., Taglialatela-Scafati, O., Tantillo, D.J., Verpoorte, R., Wang, B.G., Williams, C.M., Williams, P.G., Wist, J., Yue, J.M., Zhang, C., Xu, Z., Simmler, C, Lankin, D.C., Bisson, J., Pauli, G.F.(2018). The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Nat Prod Rep, Advance Article. DOI: 10.1039/C7NP00064B

Gibitz Eisath N., Eichberger, M., Gruber, R., Sturm, S.*, Stuppner, H. (2018). Development and validation of a rapid ultra-high performance liquid chromatography diode array detector method for Verbena officinalis L. J Pharmaceut BiomedAnal160:160-167. DOI: 10.1016/j.jpba.2018.07.047

Heilos, D., Röhrl, C., Pirker, C., Englinger, B., Baier, D., Mohr, T., Schwaiger, M., Iqbal, S.M., van Schoonhoven, S., Klavins, K., Eberhart, T., Windberger, U., Taibon, J., Sturm, S., Stuppner, H., Koellensperger, G., Dornetshuber-Fleiss, R., Jäger, W., Lemmens-Gruber, R., Berger, W. (2018). Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins. Oncotarget 9 (39):25661-25680. DOI:10.18632/oncotarget.25432

Gibitz Eisath, N., Sturm, S., Stuppner, H. (2018). Supercritical Fluid Chromatography in Natural Product Analysis – An Update (Mini-Review). Planta Med 84 (06/07):361-371. DOI:10.1055/s-0037-1599461

Ganzera, M., and Sturm, S. (2018). Recent advances on HPLC/MS in medicinal plant analysis—An update covering 2011-2016 (Review). J Pharmaceut BiomedAnal 147:211- 233 DOI:10.1016/j.jpba.2017.07.038

Hochleitner, J., Akram, M., Gostner, JM., Ueberall, M., Davis, R.A., Waltenberger, B., Stuppner, H., Sturm, S., Schuster, D., Ueberall, F. (2017). A novel combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature. Scientific reports 7; Article number: 8071. DOI:10.1038/s41598-017-08404-0

Pataczek, L., Cheilari, A., Zikeli, S., Sturm, S., Stuppner, H., Gruber, S. (2017). Centaurium erythraea Cultivation Method for Optimal Yield and Product Quality. Journal of Herbs, Spices & Medicinal Plants 23 (3):193-215. DOI:10.1080/10496475.2017.1295414

Cheilari, A., Sturm, S.*, Intelmann, D., Seger, C., and Stuppner, H. (2016). Head to Head Comparison of uHPLC-DAD versus qNMR for the Quantitative Analysis of the Silymarin Complex in Silybum marianum Fruit Extracts. J Agric Food Chem 64:1618-1626. DOI:10.1021/acs.jafc.5b05494

Taibon, J., Sturm, S., Seger, C., Strasser, H., and Stuppner, H. (2016). Combination of a QuEChERS-based extraction protocol with a fast and selective UHPLC-QTOF-MS assay for the detection and quantification of Metarhizium brunneum metabolites from honey samples. SOJ Pharmacy & Pharmaceutical Sciences 3(3):1-5. DOI:10.15226/2374-6866/4/1/00147

Skhirtladze, A. V., Benidze, M. M., Kemertelidze, E. P., Grigolava, B. L., Sturm, S., and Ganzera, M. (2015). Steroid composition of Fruit from Yucca gloriosa Introduced into Georgia. Chem Nat Compd 51:283-288. DOI:10.1007/s10600-015-1262-3

Taibon, J., Sturm, S.*, Seger, C., Strasser, H., and Stuppner, H. (2015). Quantitative Assessment of Destruxins from Strawberry and Maize in the Lower Parts per Billion Range: Combination of a QuEChERS Based Extraction Protocol with a Fast and Selective UHPLC-QTOF-MS Assay.J Agric Food Chem 63:5707−5713. DOI:10.1021/acs.jafc.5b01562

Taibon, J., Sturm, S.*, Seger, C., Werth, M., Strasser, H., and Stuppner, H. (2015). Supercritical fluid chromatography as an alternative tool for the qualitative and quantitative analysis of Metarhizium brunneum metabolites from culture broth. Planta Med 81:1736-1743. DOI:10.1055/s-0035-1557823

Aguiriano-Moser, V., Svejda, B., Li, Z.X., Sturm, S., Stuppner, H., Ingolic, E., Höger, H., Siegl, V., Allard-Meier, N., Sadjak, A., and Pfragner, R. (2015). Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells. Mol Med Rep 12:5003-5011. DOI:10.3892/mmr.2015.4053

Taibon, J., Sturm, S., Seger, C., Parth, M., Strasser, H., and Stuppner, H. (2014). Development of a fast and selective UHPLC-DAD-QTOF-MS/MS method for the qualitative and quantitative assessment of destruxin profiles.Anal Bioanal Chem406:7623–7632. DOI:10.1007/s00216-014-8203-z.

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Teaching activities

• Biogenic Drugs, VO
• Principals of phytochemical techniques, VO
• Principals of phytochemical techniques, UE
• Quality control of medicinal plants, UE
• Bachelor´s Thesis in Pharmacy, PS
• Current Aspects of Pharmacognosy, VU
• Phytopharmaceuticals - Quality Control, VU
• Working Techniques in Pharmaceutical Sciences, UE
• Pharmaceutical core subjects I, UE
• Structure Determination of Natural Products by NMR and MS, SE