Publications

Bernhard Auer

 

  1. Haberfellner H, Auer B, Gleispach H. Preliminary studies in plasma and cerebrospinal fluid cortisol in children with different diseases. Clin. Chim. Acta 54, 5-10 (1974).

  2. Wagner EF, Auer B, Schweiger M. Development of E.coli virus T1: Escape from host restriction. J. Virol. 29, 1229-1231 (1979).

  3. Auer B, Günthert U, Wagner EF, Schweiger M. Is the DNA of virus T7 methylated? J. Gen. Virol. 44, 609-613 (1979).

  4. Herrlich P, Schweiger M, Rahmsdorf HJ, Ponta H, Pfennig-Yeh M, Wolfram P, Rahmsdorf U, Auer B, Wagner EF. Virus T7-a probe of cellular control mechanisms. In FEBS 12th Meeting Dresden 1978, Gene Function 51 (Rosenthal S, Bielka H, Contalle C, Zimmer C, eds), pp. 337-346. Pergamon Press, Oxford (1979).

  5. Fabricant JD, Wagner EF, Auer B, Schweiger M. DNA-modification during differentiation in mouse teratocarcinoma cells. Exp. Cell Res. 124, 25-29 (1979).

  6. Klocker H, Auer B, Burtscher HJ, Hofmann J, Hirsch-Kauffmann M, Schweiger M. A sensitive radioimmuno assay for thymine dimers. Mol. Gen. Genet. 186, 475-477 (1982).

  7. Auer B, Klocker H, Burtscher HJ, Hirsch-Kauffmann M, Schweiger M. A sensitive assay for thymine dimers. Naturwissenschaften 69, 340-341 (1982).

  8. Auer B, Vosberg HP, Buhre U, Klocker H, Hirsch-Kauffmann M, Schweiger M. Intracellular distribution of DNA topoisomerase I in fibroblasts from Fanconi patients. Hum. Genet. 61, 369-371 (1982).

  9. Klocker H, Auer B, Burtscher HJ, Hirsch-Kauffmann M, Schweiger M. Repair rate in human fibroblasts measured by thymine dimer excorporation. Mol. Gen. Genet. 188, 309-312 (1982).

  10. Klocker H, Burtscher HJ, Auer B., Hirsch-Kauffmann M, Schweiger M. Poly-ADP-ribosylation is not required for excision of a DNA-damage. Naturwissenschaften 70, 93-94 (1983).

  11. Klocker H, Auer B, Hirsch-Kauffmann M, Altmann H, Burtscher HJ, Schweiger M. DNA repair dependent NAD+ metabolism is impaired in cells from a patient with Fanconi's anaemia. EMBO J. 2, 303-307 (1983).

  12. Wagner EF, Auer B, Schweiger M. Escherichia Coli virus T1: Genetic controls during virus infection. Curr. Top. Microbiol. Immunol. 102, 131-152 (1983).

  13. Auer B, Schweiger M. Evidence that E.coli virus T1 induces a DNA-methyltransferase. J. Virol. 49, 588-590 (1984).

  14. Klocker H, Auer B, Burtscher HJ, Hirsch-Kauffmann M, Schweiger M. A synthetic haptene for induction of thymine dimer specific antibodies. Eur. J. Biochem. 142, 313-316 (1984).

  15. Klocker H, Burtscher HJ, Auer B, Hirsch-Kauffmann M, Schweiger M. Fibroblasts from patients with Fanconi anaemia are not deficient in excision for thymine dimer. Eur. J. Cell Biol. 37, 240-242 (1985).

  16. Klocker H, Schneider R, Burtscher HJ, Auer B, Hirsch-Kauffmann M, Schweiger M. Transient expression of a plasmid gene, a tool to study DNA repair in human cells: Defect of DNA repair in Cockayne syndrome; one thymine cyclobutane dimer is sufficient to block transcription. Eur. J. Cell Biol. 39, 346-351 (1986).

  17. Burtscher HJ, Auer B, Klocker H, Schweiger M, Hirsch-Kauffmann M. Isolation of ADP-ribosyltransferase by affinity chromatography. Anal. Biochem. 152, 285-290 (1986).

  18. Schweiger M, Auer B, Burtscher HJ, Hirsch-Kauffmann M, Klocker H, Schneider R. DNA repair in human cells: biochemistry of the hereditary diseases Fanconis anaemia and Cockayne syndrome. 'Fritz-Lipmann Lecture'. Biol. Chem. Hoppe-Seyler 367, 1185-1195 (1986).

  19. Schweiger M, Auer B, Burtscher HJ, Hirsch-Kauffmann M, Klocker H, Schneider R. DNA repair in human cells: biochemistry of the hereditary diseases Fanconis anaemia and Cockayne syndrome. 'Fritz-Lipmann Lecture'. Eur. J. Biochem. 165, 235-242 (1987).

  20. Schneider R, Auer B, Kühne C, Herzog H, Klocker H, Burtscher HJ, Hirsch-Kauffmann M, Wintersberger U, Schweiger M. Isolation of a cDNA clone for human NAD+: protein ADP-ribosyltransferase. Eur. J. Cell Biol. 44, 302-307 (1987).

  21. Burtscher HJ, Schneider R, Klocker H, Auer B, Hirsch-Kauffmann M, Schweiger M. ADP-ribosyltransferase is highly conserved: purification and characterization of ADP-ribosyltransferase from a fish and its comparison with the human enzyme. J. Comp. Physiol. B 157, 567-572 (1987).

  22. Scherzer E, Auer B, Schweiger M. Identification, purification and characterization of E.coli virus T1 DNA-methyltransferase. J. Biol. Chem. 262, 15225-15231 (1987).

  23. Burtscher HJ, Klocker H, Schneider R, Auer B, Hirsch-Kauffmann M, Schweiger M. ADP-ribosyltransferase from Helix pomatia purification and characterization. Biochem. J. 248, 859-864 (1987).

  24. Haring C, Humpel C, Auer B, Saria A, Barnas C, Fleischhacker W, Hinterhuber H. Clozapine plasma levels determined by high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. 428, 160-166 (1988).

  25. Golderer G, Schneider R, Auer B, Loidl P, Gröbner P. ADP-ribosylation in isolated nucleic of Physarum polycephalum. Biochem. J. 253, 859-867 (1988).

  26. Schneider R, Schneider-Scherzer E, Thurnher M, Auer B, Schweiger M. The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module. EMBO J. 7, 4151-4156 (1988).

  27. Schweiger M, Schneider R, Hirsch-Kauffmann M, Auer B, Klocker H, Scherzer E, Thurnher M, Herzog H, Vosberg HP, Wagner EF. DNA-repair in human cells: Molecular cloning of c-DNAs coding for enzymes related to repair. In The Roots of Modern Biochemistry (Kleinkauf H, von Döhren H, Jaenicke L, eds), pp. 379-387. Walter de Gruyter, Berlin-New York (1988).

  28. Herzog H, Zabel BU, Schneider R, Auer B, Hirsch-Kauffmann M, Schweiger M. Human nuclear NAD+:protein(ADP-ribosyl)transferase: Localisation of the gene on chromosome 1q41-42 and expression of an active human enzyme in Escherichia coli. Proc. Natl. Acad. Sci. USA 86, 3514-3518 (1989).

  29. Auer B, Nagl U, Herzog H, Schneider R, Schweiger M. Human nuclear NAD+ ADP-ribosyltransferase(polymerizing): Organization of the gene. DNA 8, 575-580 (1989).

  30. Humpel C, Knaus GA, Auer B, Knaus H, Haring C, Theodorsson E, Saria A. Effects of haloperidol and clozapine on preprotachykinin-A messenger RNA, tachykinin tissue levels, release and neurokinin-1 receptors in the striato-nigral system. Synapse 6, 1-9 (1990).

  31. Schneider-Scherzer E, Auer B, de Groot EJ, Schweiger M. Primary structure of a DNA-methyltransferase from E.coli virus T1: DNA sequence, genomic organization and comparative analysis. J. Biol. Chem. 265, 6086-6091 (1990).

  32. Hirsch-Kauffmann M, Schwaiger H, Auer B, Schneider R, Herzog H, Klocker H, Schweiger M. Aging and DNA Repair. In Molecular Mechanisms of Aging (Beyreuther K, Schettler S, eds), pp. 51-59. Springer, Heidelberg (1990).

  33. Kaiser P, Auer B, Schweiger M. Inhibition of the cell cycle in Saccharomyces cerevisiae by expression of human NAD+ADP-ribosyltransferase requires the DNA binding domain. Mol. Gen. Genet. 232, 231-239 (1992).

  34. Baumgartner M, Schneider R, Auer B, Herzog H, Schweiger M, Hirsch-Kauffmann M. Fluorescence in situ mapping of the human nuclear NAD+ADP-ribosyl-transferase gene and two secondary sites to human chromosomal bands 1q42, 13q34 and 14q24. Cytogenet. Cell. Genet. 61, 172-174 (1992).

  35. Flick K, Schneider R, Auer B, Hirsch-Kauffmann M, Schweiger M. No abnormalities in the NAD+ADP-ribosyltransferase (polymerizing) gene of transformed cells from a Fanconi´s anemia patient. Hum. Genet. 89, 690-691 (1992).

  36. Berghammer H, Schweiger M, Auer B. Structure and organization of the mouse pADPRT gene. In ADP-Ribosylation Reactions (Poirier GG, Moreau P, eds), pp. 69-72. Springer, New York (1992).

  37. Schweiger M, Auer B, Herzog H, Hirsch-Kauffmann M, Kaiser P, Flick K, Nagl U, Schneider R. Molecular biology of human nuclear NAD+: ADP-Ribosyl-transferase (polymerizing). In ADP-Ribosylation Reactions (Poirier GG, Moreau P, eds), pp. 20-29. Springer, New York (1992).

  38. Kaiser P, Auer B. Rapid shuttle plasmid preparation from yeast cells. Biotechniques 14, 552 (1993).

  39. Berghammer H, Auer B. 'Easypreps': Fast and easy plasmid minipreparation for analysis of recombinant clones in E. coli. Biotechniques 14, 527-528 (1993).

  40. Kofler B, Wallraff E, Herzog H, Schneider R, Auer B, Schweiger M. Purification and characterization of NAD+:ADP-ribosyltransferase(polymerizing) from Dictyostelium discoideum. Biochem. J. 293, 275-281 (1993).

  41. Ritsch A, Auer B, Föger B, Schwarz S, Patsch JR. Polyclonal-antibody-based immunoradiometric assay for quantificaton of cholesteryl ester transfer protein. J. Lipid Res. 34, 673-679 (1993).

  42. Herzog H, Baumgartner M, Vivero C, Selbie LA, Auer B, Shine J. Genomic organization, localization and allelic differences in the gene for the human blood pressure regulating neuropeptide Y Y1 receptor. J. Biol. Chem. 268, 6703-6707 (1993).

  43. Fritz G, Auer B, Kaina B. Effect of human poly(ADP-ribose)polymerase in Chinese hamster cells on mutagen resistance. Mutat. Res. 308, 127-133 (1994).

  44. Oei SL, Herzog H, Hirsch-Kauffmann M, Schneider R, Auer B, Schweiger M. Transcriptional regulation and autoregulation of the human gene for ADP-ribosyltransferase. Mol. Cell. Biochem. 138, 99-104 (1994).

  45. Kaiser P, Mansour HA, Greeten T, Auer B, Schweiger M, Schneider R. The human ubiquitin-conjugating enzyme UbcH1 is involved in the repair of UV-damaged, alkylated and cross-linked DNA. FEBS Lett. 350, 1-4 (1994).

  46. Lechleitner M, Auer B, Zilian U, Hoppichler F, Schirmer M, Föger B, Geisen F, Patsch JR, Konwalinka G. The immunosuppressive substance 2-chloro-2-deoxyadenosine modulates lipoprotein metabolism in a murine macrophage cell line (P388 cells). Lipids 29, 627-633 (1994).

  47. Wang ZQ, Auer B, Stingl L, Berghammer H, Haidacher D, Schweiger M, Wagner EF. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev. 9, 509-520 (1995).

  48. Auer B, Flick K, Wang ZQ, Haidacher D, Jäger S, Berghammer H, Kofler B, Schweiger M, Wagner EF. On the role of ADPRT, the nuclear polymerizing NAD+:protein-(ADP-ribosyl)transferase in Dictyostelium discoideum and in mice. Biochimie 77, 444-449 (1995).

  49. Schweiger M, Oei SL, Herzog H, Menardi C, Schneider R, Auer B, Hirsch-Kauffmann M. Regulation of the human poly(ADP-ribosyl)transferase promoter via alternative DNA racket structures. Biochimie 77, 480-485 (1995).

  50. Windisch JM, Marksteiner R, Lang ME, Auer B, Schneider R. Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 bind to a single leucine-rich motif of TrkB. Biochemistry 34, 11256-11263 (1995).

  51. Windisch JM, Auer B, Marksteiner R, Lang ME, Schneider R. Specific neurotrophin binding to leucin-rich motif peptides of TrkA and TrkB. FEBS Lett. 374, 125-129 (1995).

  52. Zhang J, Ziegler M, Schneider R, Klocker H, Auer B, Schweiger M. Identification and purification of a bovine liver mitochondrial NAD+-glycohydrolase. FEBS Lett. 377, 530-543 (1995).

  53. Ziegler M, Jorcke D, Zhang J, Schneider R, Klocker H, Auer B, Schweiger M. Characterization of detergent solubilized beef-liver mitochondrial NAD+ glycohydrolase and its truncated hydrosoluble form. Biochemistry 35, 5207-5212 (1996).

  54. Menardi C, Schneider R, Kaspar F, Klocker H, Hirsch-Kauffmann M, Auer B, Schweiger M. Identification of a splice-site mutation in a patient with complete deficiency of adenine phosphoribosyltransferase (APRT). Hum. Mutat. 10, 251-255 (1997).

  55. Egle A, Villunger A, Kos M, Böck G, Gruber J, Auer B, Greil R. Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-alpha2. Eur. J. Immunol. 26, 3119-3126 (1996).

  56. Teaumroong N, Schwarzer C, Auer B, Haselwandter K. A nonradioactive DNA probe for detecting dicyandiamide-degrading soil bacteria. Biol. Fertil. Soils 25, 159-162 (1996).

  57. Geley S, Hartmann BL, Kapelari K, Egle A, Villunger A, Haidacher D, Greil R, Auer B, Kofler R. The interleukin 1ß-converting enzyme inhibitor CrmA prevents Apo1/Fas- but not glucocorticoid-induced poly(ADP-ribose)polymerase cleavage and apotosis in human lymphoblastic leukemia cells. FEBS Lett. 402, 36-40 (1997).

  58. Geley S, Hartmann BL, Hattmannstorfer R, Loffler M, Ausserlechner MJ, Bernhard D, Sgonc R, Strasser-Wozak EM, Ebner M, Auer B, Kofler R. p53-induced apoptosis in the human T-ALL cell line CCRF-CEM. Oncogene 15, 2429-2437 (1997).

  59. Gassner C, Schneider-Scherzer E, Lottspeich F, Schweiger M, Auer B. Escherichia coli bacteriophage T1 methyltransferase appears to interact with Escherichia coli enolase. Biol. Chem. 379, 621-623 (1998).

  60. Nie J, Ota K, Morisawa K, Auer B, Schweiger M, Taniguchi T. Analysis of TPA-regulatory element(s) in the genomic poly(ADP-ribose) synthetase gene in human leukemia U937 Cells. Biochemistry 37, 14181-14188 (1998).

  61. Althaus FR, Kleczkowska HE, Malanga M, Müntener CP, Pleschke JM, Ebner M, Auer B. Poly ADP-ribosylation: A DNA break signal mechanism. Mol. Cell. Biochem. 193, 5-11 (1999).

  62. Hartmann BL, Geley S, Löffler M, Hattmannsdorfer R, Strasser-Wozak EMC, B. Auer B, Kofler R. Bcl-2 interferes with the execution phase, but not upstream events, in glucocorticoid-induced leukemia apoptosis. Oncogene 18, 713-719 (1999).

  63. Berghammer H, Ebner M, Marksteiner R, Auer B. pADPRT-2: A novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans. FEBS Lett. 449, 259-63 (1999).

  64. Rollinger-Holzinger I, Eibl B, Pauly M, Griesser U, Hentges F, Auer B, Pall G, Schratzberger P, Niederwieser D, Weiss, Zwierzina H. LST1: A gene with extensive alternative splicing and immunomodulatory function. J. Immunol. 164, 3169-3176 (2000).

  65. Herceg Z, Pétrilli V, Wutz A, Auer B, Cros M-P, Wang Z-Q. Functional testing of human PARP in proliferation, endotoxic shock and radiosensitivity: A genetic rescue study. In PARP as a Therapeutic Target (Zhang J, ed), pp. 67 – 81. CRC Press, Boca Raton (2002).

  66. Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P. A tandem affinity tag for two-step purification under fully denaturing conditions: Application in ubiquitin profiling and protein complex identification combined with in vivo cross-linking. Mol. Cell. Proteomics 5, 737-48 (2006).

  67. Tagwerker C, Zhang H, Wang X, Larsen LS, Lathrop RH, Hatfield GW, Auer B, Huang L, Kaiser P. HB tag modules for PCR-based gene tagging and tandem affinity purification in Saccharomyces cerevisiae. Yeast 23, 623-632 (2006).

  68. Achmüller C, Werther F, Wechner P, Auer B. Synthesis of genes with multiple identical domains. Biotechniques 42, 43-46 (2007).

  69. Achmüller C, Kaar W, Ahrer K, Wechner P, Hahn R, Werther F, Schmidinger H, Cserjan-Puschmann M, Clementschitsch F, Striedner G, Bayer K, Jungbauer A, Auer B. N(pro) fusion technology to produce proteins with authentic N termini in E. coli. Nat. Methods 4, 1037-1043 (2007).

  70. Paal M, Heel T, Schneider R, Auer B. A novel Ecotin-Ubiquitin-Tag (ECUT) for efficient, soluble peptide production in the periplasm of Escherichia coli. Microb. Cell Fact. 8:7 (2009).

  71. Kaar W, Ahrer K, Dürauer A, Greinstetter S, Sprinzl W, Wechner P, Clementschitsch F, Bayer K, Achmüller C, Auer B, Hahn R, Jungbauer A. Refolding of Npro fusion proteins. Biotechnol Bioeng. 104(4): 774-84(2009).

  72. Heel T, Paal M, Schneider R, Auer B. Dissection of an old protein reveals a novel application: domain D of Staphylococcus aureus Protein A (sSpAD) as a secretion-tag. Microb. Cell Fact. 9, 92 (2010).

  73. Heel T, Vogel GF, Lammirato A, Schneider R, Auer B. FlgM as a Secretion Moiety for the Development of an Inducible Type III Secretion System.  PLoS ONE 8, e59034 (2013).

  74. Zögg T, Sponring M, Schindler S, Koll M, Schneider R, Brandstetter H, Auer B. Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis. Structure 21, 1-10 (2013).

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