Matthias Rainer
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Research Focus
The main focus of my work is to expand the scope of unique and high performance analytical techniques, based on nano- and micro-structured materials like diamond, metal-oxides and synthetic polymers. The use of these materials in the discovery of diagnostic markers for various kinds of diseases (e.g. cancer) is achieved from peptide/protein mass fingerprints of biofluids like serum, by employing matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). Identification of peptides is carried out by eluting bound biomolecules from the carrier material and subjecting them to high resolution µ-HPLC separation including enrichment and fractionation, followed by MS/MS fragmentation.
Diploma-Thesis
Diploma-Thesis at the Division of Biomedical Physics, (Innsbruck Medical University, Austria). “Spectral Measurements of the Optical Thickness of Atmospheric Aerosols in Innsbruck and surrounding Area from January to December 2002” (2003).
PhD-Thesis
PhD-Thesis at the Institute of Analytical Chemistry and Radiochemistry with Prof. Günther Bonn (University of Innsbruck). “Mass Spectrometric Identification of Biomolecules Employing Poly(glycidyl methacrylate/divinyl benzene) Based Adsorbents” (2007).